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TITLE:

ASSOCIATION BETWEEN BMI AND CORONARY ARTERY DISEASE SEVERITY IN FEMALES OF PAKISTANI ORIGIN

AUTHORS:

Dr. Shaista Akbar, Dr. Samim Azizi, Dr. Madiha Safdar

ABSTRACT:

Aim: To assess the relationship between BMI and the severity of coronary heart disease in the Pakistani women population. Project: An Observational cross-sectional study. Place and duration of the study: In the Department of Cardiology, Jinnah Hospital Lahore for one year duration from January 2019 to January 2020. Patients and methods: 132 women undergoing coronary angiography were included in the study population. Obesity was classified as Normal (BMI 21-24 kg / m2), overweight (BMI 25-29 kg / m2), obesity class I (BMI 30-34) according to BMI according to the criteria of the National Institutes of Health (NIH) kg / m2), obesity class II (BMI 35-39 kg / m2 and obesity class III (BMI 40 or more kg / m2). Coronary angiography data was obtained from Siemens Queries software, which contains a database containing detailed results of angiographic tests of all patients in this institution. Significant lesions were defined as those that narrowed> 70% of the coronary artery diameter (> 50% for the left main coronary artery). We tried to measure "CAD severity" by determining the incidence of high-risk coronary anatomy (HRCA,> 50% left main coronary artery stenosis and / or significant coronary artery disease). Results: Comparing overall obese (BMI ≥ 30) vs. non obese groups, a statistically significant low prevalence of HRCA was encountered in the obese group (26 of 56, 46.4% vs. 54 of 76, 79.5% p < 0.05) Conclusion: We conclude that obesity is associated with less serious coronary heart disease in Pakistani women. Key words: obesity, coronary artery disease severity, coronary angiography.

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