- CODEN : IAJPBB
- issn 2349-7750
TITLE:
NON-INVASIVE VALUATION OF ESOPHAGEAL VARICES IN PATIENTS WITH LIVER CIRRHOSIS
AUTHORS:
Dr Muhammad Zulqarnain, Dr Sahrish Batool, Dr Sidra Shaheen
ABSTRACT:
Aim: To study the effectiveness of 6 non-invasive methods in the evaluation of the presence of esophageal varices in chronic liver disease (CLD). Design: A prospective study of patients with chronic liver disease to detect the presence or absence of esophageal varices using non-invasive tests. Place and Duration: In the Gastroenterology Department of Services Hospital Lahore for one year duration from March 2019 to March 2020. Methods: Consecutive patients with clinical and para- clinical criteria of CLD with no upper GIT bleeding at presentation or in their past history were included in this study. Results: During the study 103 patients with CLD met the inclusion criteria and were enrolled in this study, 60 were men and 43 women. The age ranged from 16 to 81 years, with an average age of 42.69 ± 16.96 years. Of these 103 patients, 62 (59.95%) had esophageal varices, 36 (58%) were small and 26 (42%) were large. Sensitivity, specificity, PPV and NPV values of 6 examined paraclinical and biochemical variables were evaluated. The sensitivity and the specificity for spleen diameter was 79.7% and 33.3% respectively, for platelet count 26.6% and 87.2%, for P.V diameter 39% and 47.4%, for Rt. lobe diameter/albumin ratio 23.4% and 82%, for spleen diameter/platelet count ratio 37.5% and 74.4% and for AST/ALT ratio 53.1% and 51.3%. Conclusion: No one of the studied non-invasive tests had high predictive value or high sensitivity or specificity for prediction of esophageal varices, consequently upper GIT endoscopy is still the gold standard way in the diagnosis and grading of esophageal varices. Key words: esophageal varices, non-invasive tests, EPC, Pakistan
FULL TEXT
Approved Journal
NLM ID:101711216 [Serial]
Included in EuroPub database
ICV 2015 - 61.16
Indexed In
S.J Impact Factor:7.157
cosmos Impact Factor:4.153
ICMJE Recommendations
IP Indexing Impact Factor: 2.76
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