Volume : 11, Issue : 08, August – 2024
Title:
A SURVEY ON ASSESSING THE KNOWLEDGE ATTITUDE AND PRACTICE OF NSAIDS IN COMMUNITY PHARMACIES IN THE SOUTHERN PART OF KERALA
Authors :
Dr. Nithin Manohar R* Jeberson J, Jerin S Sam, Muhammed Bilal N, Saleema A H, Shibunish Mon N, Dr. Prasobh G R
Abstract :
Background: A survey was conducted to evaluate the knowledge, attitude, and practice (KAP) regarding nonsteroidal anti-inflammatory drugs (NSAIDs) in community pharmacies in the southern part of Kerala.
Methods: This prospective observational study involved community pharmacies in southern Kerala. We assessed KAP related to NSAIDs using a specifically designed questionnaire.
Conclusion: The study revealed that knowledge about NSAIDs among pharmacists in Kerala is below average. Out of 100 randomly selected community pharmacies, it was found that pharmacists over the age of 45 generally lacked updated knowledge about NSAIDs, including new guidelines and potential side effects. Many pharmacists, primarily holding a Diploma in Pharmacy (D Pharm), were aware of NSAIDs use but were less informed about associated risks. NSAIDs such as acetaminophen and ibuprofen were often dispensed without a prescription, while others required one. Initially, the KAP regarding NSAIDs in these pharmacies was subpar. However, following targeted counseling through informational leaflets, an improvement in KAP was observed. This emphasizes the importance of continuous education and counseling for pharmacists to enhance the safe use of NSAIDs. Effective communication of risk factors and side effects significantly improved pharmacists’ understanding and practice. The study underscores the crucial role of pharmacists in ensuring safe NSAID use and the positive impact of educational interventions on their knowledge and practices.
Keywords: KAP, Questionnaire, Community Pharmacy
Cite This Article:
Please cite this article in press Nithin Manohar R et al A Survey On Assessing The Knowledge Attitude And Practice Of Nsaids In Community Pharmacies In The Southern Part Of Kerala.,Indo Am. J. P. Sci, 2024; 11 (08).
Number of Downloads : 10
References:
1. K.D Tripathi, Essentials of medical pharmacology, sixth edition page no: 184-201.
2. Wisam AL Masoudi et al (2023): Knowledge and practice reporting the use of NSAIDs among university students in Jordon. 2023; 114-121.
3. Qi SHOU et al (2022): Concerns that the use of non-steroidal anti-inflammatory drugs NSAIDs 2022; 634-651.
4. Rebekah Brennan et al (2021): A Scoping review of non-medical and extra medical use of NSAIDs 2021; 44 (9) :917-923.
5. Jennifer S Davis (2017): Use of NSAIDs in UC Adults changes overtime by demographic.2017;213-218.
6. Montinar M.R., et al: The first 3500years of aspirin history from its roots – A concise summary. Yase. Pharmacology. 2019; 113:1-8.
7. Tsutsumi S., et al: Endoplasmic reticulum stress response is involved in nonsteroidal anti- inflammatory drug-induced apoptosis. Cell Death Differ. 2004;119):1009-1016.
8. Gupta A., et al: NSAIDs in the Treatment of Postoperative Pain. Curr. Pain Headache Rep. 2016;20(11):62.
9. Budoff P.W. Use of mefenamic acid in the treatment of primary dysmenorrhea. JAMA. 1979;241(25):2713-2716.
10. Rao C.V., et al: Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti- inflammatory agent. Cancer Res. 1995;55(7):1464-1472.
11. Amici C., et al: Indomethacin has a potent antiviral activity against SARS coronavirus. Antiviral Ther. 2006;11(8):1021-1030.
12. James D.S. The multisystem adverse effects of NSAID therapy. J. Am. Osteopath. Assoc. 1999:99(11 Suppl): S1-57.
13. Dreischulte T., et al: Combined use of nonsteroidal anti-inflammatory drugs with diuretics I and or renin-angiotensin system inhibitors in the community increases the risk of acute kidney injury. Kidney Int. 2015;88(2):396 403.
14. Becker J.C., et al: Current approaches to prevent NSAID-induced gastropathy-COX selectivity and beyond. Br: J. Clin. Pharmacology. 2004;58(6):587-600.
15. Bjarnason I., et al: Mechanisms of Damage to the Gastrointestinal Tract from Nonsteroidal Anti-Inflammatory Drugs. Gastroenterology. 2018;154(3):500-514.
16. Wallace J.L., et al: Emerging roles for cyclooxygenase-2 in gastrointestinal mucosal defense. Br. J. Pharmacology. 2005:145(3):275-282.
17. Hollingworth P. et al: The use of non-steroidal anti-inflammatory drugs in pediatric rheumatic diseases. 1993; 32:73-77.
18. Davidson KW, et al: Aspirin use to prevent cardiovascular disease: us preventive services task force recommendation statement. 2022; 327:1577- 1584.
19. Harirforeosh S, et al: Adverse effects of nonsteroidal anti-inflammatory drugs: an update of gastrointestinal, cardiovascular and renal complications. Pharm Sci. 2013; 16:821-847.
20. Bjorkman D. et al: Nonsteroidal anti-inflammatory drug-associated toxicity of the liver, lower gastrointestinal tract, and esophagus. 1998; 105:17-21.
21. Huepa YY, et al: Short- and long-term effects of NSAIDs on the gastrointestinal mucosa: complex analysis of benefits and complications prevention. 2021; 74:1011-1018.
22. Sostres C, et al: Adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs, aspirin and coxibs) on upper gastrointestinal tract. 2010:24:121- 132.
23. Watanabe T, et al: Current knowledge on non-steroidal anti-inflammatory drug-induced small- bowel damage: a comprehensive review. 2020; 55:481–495.
24. Fort Fort, et al: Celecoxib, a COX-2–specific inhibitor: the clinical data. 1999; 28:13–18.
25. Nithin Manohar R: A textbook of community pharmacy,2021.
26. Teichert M et al: Effectiveness by community pharmacist of NSAIDs Pharmacoepidemiology Drug Safety. 2014 Apr;2023(4):382-391.