Volume : 11, Issue : 08, August – 2024
Title:
PROSPECTIVE OBSERVATIONAL STUDY ON DRUG UTILIZATION REVIEW FOR CARDIOVASCULAR DISEASES IN TERTIARY CARE TEACHING HOSPITAL
Authors :
Mahe Naaz Sultana, Samia Mohsin Shareef, Late Mir Kashif Ali, Hasan Ali Khan Walajahi, Syed Abrar Ali, Dr. Syeda rana nikhat
Abstract :
Background: CVD remains the most non-communicable reasons for death and its prevalence is increasing nowadays. DUR plays an important role in helping the health care systems understand, clarify and improve the prescribing pattern, medication use.
Aims And Objectives: The objectives of this study are to observe types of Cardiovascular Diseases (CVD) and find out its prevalence, to review risk factors and co-morbidities contributing to worsening of CVD among the patients. This study aims to analyse the prescribing patterns of CVD drugs, track drug-drug interactions and any Adverse Drug Reactions (ADR) as well as to determine patient’s compatibility to medication adherence.
Methodology: A prospective observational study was carried out at tertiary care teaching hospital over the course of six months. Study included patients with age above 18 years of either sex or any co-morbidity; patients with symptoms possibly related to CVD and receiving continuous care. Patients with coagulation disorders with bleeding manifestations, malignancies, congenital diseases, COVID -19, pregnant and nursing mothers, uncooperative and unconscious patients and who reported using indigenous medications were excluded.
Results: A total of 118 cases were collected, consisting of 60 females (50.84%) and 58 males (49.15%). Patients in the age group of 51-60 years (26.27%) were most afflicted. The two most prevalent diseases in the study were CVA (31.35%) and CAD (20.33%). The most universal risk factors and co-morbidities were hypertension (70.33%) and diabetes mellitus (38.13%). Alcohol (33%) and smoking abuse (16.94%) were the next prevailing factors. Statins (71.18%), anti-platelets (70.33%) and diuretics (57.62%) were commonly prescribed drugs. Possible drug-drug interactions were listed. Drugs prescribed from NLEM and in generic at lower rates, and polypharmacy was evident which led to injection and antibiotic overuse, according to standard values of WHO indicators. Majority of patients were medium (50.84%) to low (39.83%) adherent to medications. Using Naranjo scale, ADRs were assessed.
Conclusion: CVD is on rise in patients owing primarily to lifestyle habits, followed by risk factor contribution and low compliance to medications. DUR using WHO indicators aided in observing the prescribing trends of drugs, polypharmacy which ultimately led to high probability of drug interactions, ADR and drug misuse.
Keywords: Cardiovascular diseases, Drug utilisation review, polypharmacy.
Cite This Article:
Please cite this article in press Mahe Naaz Sultana et al., Prospective Observational Study On Drug Utilization Review For Cardiovascular Diseases In Tertiary Care Teaching Hospital., Indo Am. J. P. Sci, 2024; 11 (08).
Number of Downloads : 10
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