Volume : 11, Issue : 12, December – 2024
Title:
FORMULATION & EVALUATION OF ENTERIC-COATED CAPSULES FOR THE TREATMENT OF ULCERATIVE COLITIS
FORMULATION & EVALUATION OF ENTERIC-COATED CAPSULES FOR THE TREATMENT OF ULCERATIVE COLITIS
Authors :
K.Tejaswini, D.Raj kumar
Abstract :
As part of this investigation, budesonide sustain-release micro tablets in capsule form were created and refined to treat ulcerative colitis. Cross povidone and HPMC K4 M were used as release retardants in the direct compression method used to create Budesonide micro tablets. FTIR spectroscopy indicates that the generated formulations do not exhibit any indication of drug-excipient interaction. The constructed micro pills’ physicochemical characteristics were good. It was discovered that formulation BF4 was the best optimized when all of the formulas were examined. As per the previously reported results, capsules are able to withstand acidic pH levels and retain their structural integrity. It was shown that capsules were the most effective choice for enteric drug delivery systems.
Keywords: Budesonide, Sustain-release, Ulcerative colitis, Enteric-coated, Capsules.
Cite This Article:
Please cite this article in press Devara Raj kumar et al., Formulation & Evaluation Of Enteric-Coated Capsules For The Treatment Of Ulcerative Colitis.,Indo Am. J. P. Sci, 2024; 11 (12).
Number of Downloads : 10
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