Volume : 12, Issue : 01, January – 2025
Title:
GREEN SYNTHESIS OF COPPER NANOPARTICLE USING CURCUMA LONGA (TURMERIC) PEEL EXTRACTS IT’S PHYTOCHEMICAL, ANTI- MICROBIAL AND ANTIOXIDANT STUDIES
Authors :
Nikita D. Kharate, Vaibhav P. Gote , Dr. Swati P. Deshmukh
Abstract :
Production of Nanoparticles using rhizomes is a new area of interest. Curcuma longa (Turmeric) peel extract was used for biosynthesis of copper Nanoparticles. Green synthesis of copper Nanoparticles is is considered as an eco-friendly method using materials from rhizomes and other natural sources without using any harmful chemicals. It is a medicinal plant extensively used in ayurveda, unani, siddha medicine as a home remedy for various diseases including biliary disorders, anorexia, cough, diabetic wounds, hepatic disorder, rheumatism, and sinusitis. It has many medicinal values such as antioxidant activity, cardiovascular activity, anti- inflammatory and antimicrobial effect. Present work discuss about the green synthesis of copper Nanoparticles using curcuma longa peel extract, it’s characterization by phytochemical, antimicrobial and antioxidant studies. Curcuma longa peel extract also subjected to phytochemical screening. The active constituents present in peel extract were identified as alkaloids, glycosides, phenolics, flavonoids, proteins and carbohydrates. Lambda max was performed by uv visible spectrometer, absorption peak was observed at 420nm which is specific for copper Nanoparticles. The antimicrobial properties of the particles were determined using agar well diffusion and disc diffusion method using streptococci.
Keywords: Nanoparticles synthesis, copper Nanoparticles, phytochemical studies, antimicrobial activity, antioxidant activity.
Cite This Article:
Please cite this article in press Nikita D. Kharate et al., Green Synthesis Of Copper Nanoparticle Using Curcuma Longa (Turmeric) Peel Extracts It’s Phytochemical, Anti- Microbial And Antioxidant Studies.,Indo Am. J. P. Sci, 2025; 12 (01).
Number of Downloads : 10
References:
1. Y. Wang, X. He, K. Wang, X. Zhang, W. Tan, Barbated Skullcup herb extractmediated Biosynthesis of gold nanoparticles and its primary application in electrochemistry, ColLoids Surf. B. 73 (2009) 75–79.
2. G.O. Akintayo, A. Lateef, M.A. Azeez, T.B. Asafa, I.C. Oladipo, J.A. Badmus, S.A. Ojo,J.A. Elegbede, E.B. Gueguim-Kana, L.S. Beukes,
T.A. Yekeen, Synthesis, bioactivities And cytogenotoxicity of animal fur-mediated silver nanoparticles, IOP Conf. Ser.:Mater. Sci. Eng. 805 (2020) 012041.
3. G. Sathishkumar, C. Gobinath, K. Karpagam, V. Hemamalini, K. Premkumar, S.Sivaramakrishnan, Phyto-synthesis of silver nanoscale particles using Morinda citrifolia L. and its inhibitory activity against human pathogens, Colloids Surf. B. 95 (2012) 235–240.
4. A. Dzimitrowicz, P. Jamroz, G.C. di Cenzo, I. Sergiel, T. Kozlecki, P. Pohl, Preparation
And characterization of gold nanoparticles prepared with aqueous extracts of Lamiaceae Plants and the effect of follow up treatment with atmospheric pressure glow Microdischarge, Arab. J. Chem. (2016)https://doi.org/10.1016/j.arabjc.2016.04.004.I.C. Oladipo, A. Lateef, M.A. Azeez, T.B. Asafa, T.A. Yekeen, S.B. Ogunsona, H.M. Irshad S.H. Abbas, Antidiabetic properties of phytosynthesized gold nanoparticles (AuNPs) From Datura stramonium seed, IOP Conf. Ser.: Mater. Sci. Eng. 805 (2020) 012035.
5. A.D. Dwivedi, K. Gopal, Biosynthesis of silver and gold nanoparticles using Chenopodium album leaves extract, Colloids Surf. A Physicochem. Eng. Asp. 369 (2010) 27–33.
6. H. Lallawmawma, G. Sathishkumar, S. Sarathbabu, S. Ghatak, S. Sivaramakrishnan, G. Gurusubramanian, N.S. Kumar, Synthesis of silver and gold nanoparticles using
Jasminum nervosum leaves extract and its larvicidal activity against filarial and
Arboviral vector Culex quinquefasciatus say (Diptera: Culicidae), Environ. Sci. Pollut. Res. 22 (2015) 17753–17768.
7. S. Gurunathan, J. Han, J.H. Park, J.H. Kim, A green chemistry approach for synthesizing Biocompatible gold nanoparticles, Nanoscale Res. Lett. 9 (2014) 248.
8. P. Kuppusamy, M.M. Yusoff, G.P. Maniam, N. Govindan, Biosynthesis of metallic nanoparticles using plant derivatives and their new avenues in pharmacological applications- an updated report, Saudi Pharm. J. 24 (2016) 473–484.
9. G. Sathishkumar, P.K. Jha, V. Vignesh, C. Rajkuberan, M. Jeyaraj, M. Selvakumar, R.
Jha, S. Sivaramakrishnan, Cannonball fruit (Couroupita guianensis, Aubl.) extract Mediated synthesis of gold nanoparticles and evaluation of its antioxidant activity, J. Mol.Liq. 215 (2016) 229–236.
10. S. Iravani, Green synthesis ofmetal nanoparticles using plants, Green Chem. 13 (2011)2638–2650 646.
11. C. Jayaseelana, R. Ramkumar, A.A. Rahumana, P. Perumalb, Green synthesis of gold
Nanoparticles using seed aqueous extract of Abelmoschus esculentus and its antifungal Activity, Ind. Crop. Prod. 45 (2013) 423–429.
12. X. Huang, H. Wu, X. Liao, B. Shi, One-step, size-controlled synthesis of gold nanopartiCles at room temperature using plant tannin, Green Chem. 12 (2010) 395–399.
13. A. Dzimitrowicz, S. Berent, A. Motyka, P. Jamroz, K. Kurcbach, W. Sledz, P. Pohl, ComParison of the characteristics of gold nanoparticles synthesized using aqueous plant exTracts and natural plant essential oils of Eucalyptus globulus and Rosmarinus officinalis,Arab. J. Chem. (2016)https://doi.org/10.1016/j.arabjc.2016.09.007.
14. A. Yasmin, R. Kumaraswamy, S. Rajeshkumar, Optimization and stabilization of gold Nanoparticles by using herbal plant extract with microwave heating, Nano Converg. 1(2014) 1–7.
15. M.Nasrollahzadeh, S. Mohammad Sajadi, M. Khalaj, RSC Adv. 4 (2014)47313-47319.
16. D. Brumbaugh, A.Katelyn Cohen, K.Sarah, St. Angelo, ACS Sustainable Chem. Eng. 28 (2014) 1933-1939.
17. P.Kaur, T.Rajesh, A. Chaudhury, Green chemistry letters and reviews. 9 (2016) 33–38.
18. A.Kumar, Chatterjee, R. Chakraborty, T. Basu, Nanotechnology IOP Publishing 25 (2014) 135101.
19. Q. Lv, B. Zhang, X. Xing, Y. Zhao, R. Cai, W. Wang, Q. Gu, Journal of Hazardous Materials 347 (2018)141–149.
20. M. Reddeppa, R. C. K. Reddy, Y. Paul raj, T. Shobha rani, Asian Journal of Chemistry 31 (2019) 622-626.
21. R. Hassanien, Z. Dalal Z. Husein, F. Mostafa, A. Hakkani, Heliyon 4 (2018) 1-21.
22. S. Rajeshkumar, L.V. Bharath, Mechanism of plant-mediated synthesis of silver nanoparticles – a review on biomolecules involved, characterisation and anti- bacterial activity, Chem. Biol. Interact. 273 (2017) 219–227, http://dx.doi.org/10.1016/j.cbi.2017.06.019.
23. R. Ramanathan, A.P.O. Mullane, R.Y. Parikh, P.M. Smooker, S.K. Bhargava, V. Bansal, Bacterial kinetics-controlled shape-directed biosynthesis of silver na-
Noplates using morganella psychrotolerans, 27 (2011) 714–719. Doi:10.1021/la1036162.
24. J. Huang, L. Lin, Q. Li, D. Sun, Y. Wang, Y. Lu, N. He, K. Yang, X. Yang, H. Wang, W. Wang, W. Lin, Continuous-flow biosynthesis of silver nanoparticles by
Lixivium of sundried cinnamomum camphora leaf in tubular microreactors, (2008) 6081–6090.
25. J. Santhoshkumar, S. Rajeshkumar, S. Venkat Kumar, Phyto-assisted synthesis, characterization and applications of gold nanoparticles – a review, Biochem.
Biophys. Rep. 11 (2017) 46–57, http://dx.doi.org/10.1016/j.bbrep.2017.06.004.
26. S. Rajeshkumar, Green synthesis of different sized antimicrobial silver nanoparticles using different parts of plants – a review, 9 (2016) 197– 208.
27. P. Zhao, N. Li, D. Astruc, State of the art in gold nanoparticle synthesis, Coord. Chem. Rev. 257 (2013) 638–665,
http://dx.doi.org/10.1016/j.ccr.2012.09.002.
28. R. Dastjerdi, M. Montazer, A review on the application of inorganic nano-structured materials in the modification of textiles: focus on anti- microbial properties, ColloidsSurf. B 79 (2010) 5–18,
http://dx.doi.org/10.1016/j.colsurfb.2010.03.029.
29. P. Kaur, R. Thakur, A. Chaudhury, Biogenesis of copper nanoparticles using peel extract of Punica granatum and their antimicrobial activity against opportunistic
Pathogens, Green Chem. Lett. Rev. 9 (2016) 33–38, http://dx.doi.org/10.1080/17518253.2016.1141238.
30. S. Harne, A. Sharma, M. Dhaygude, S. Joglekar, K. Kodam, M. Hudlikar, Novel route for rapid biosynthesis of copper nanoparticles using aqueous extract of
Calotropis procera L. latex and their cytotoxicity on tumor cells, ColloidsSurf. B95 (2012) 284–288, http://dx.doi.org/10.1016/j.colsurfb.2012.03.005.
31. S.M. Hoseini, A. Hedayati, A. Taheri Mirghaed, M. Ghelichpour, Toxic effects of copper sulfate and copper nanoparticles on minerals, enzymes, thyroid hormones
And protein fractions of plasma and histopathology in common carp Cyprinus carpio, Exp. Toxicol. Pathol. 68 (2016) 493–503, http://dx.doi.org/10.1016/j.etp.
2016.08.002.
32. H.J. Lee, G. Lee, N.R. Jang, J.H. Yun, J.Y. Song, B.S. Kim, Biological synthesis of copper nanoparticles using plant extract, Une 13 (2016) 15.