Volume : 12, Issue : 01, January – 2025
Title:
FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES BY USING PREGABALIN
Authors :
Dr.K.L.Senthilkumar *, P.D. Gokulan *, M.Darshini*, R.Dhivyabharathi*, B.Sreedhar*, S. Hariprasath*
Abstract :
The present study aimed to develop and evaluate transdermal patches of Pregabalin using Hdroxy propyl methyl cellulose (HPMC) and ethyl cellulose (EC) as polymers and Polyethylene glycol (PEG) as permeation enhancer , Propylene glycol (PG) as plasticizer. Pregabalin is an anticonvulsant and analgesic agent commonly used to treat epilepsy, neuropathic pain and fibromyalgia. Transdermal patches were prepared by Solvent evaporation method and evaluated for physiochemical properties like film thickness, weight variation, folding endurance, moisture content and drug content. The result suggest that the developed transdermal patches of Pregabalin could provide a promising alternative to oral administration, offering improved bioavailability, reduced sideeffect ,enhanced patient compliance.
Key words: Transdermal patches, Pregabalin, Hydroxy propyl methyl cellulose, Propylene glycol
Cite This Article:
Please cite this article in press K.L.Senthilkumar et al., Formulation And Evaluation Of Transdermal Patches By Using Pregabalin.,Indo Am. J. P. Sci, 2025; 12 (01).
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