Volume : 12, Issue : 01, January – 2025
Title:
A REVIEW: OVERVIEW OF ANTI-CANCER HERBAL DRUG
Authors :
Vaishnavi Surve, Vaishnavi Gawande , Vinayak katekar, Dr. Swati Deshmukh
Abstract :
Cancer are chemopreventive agent , may of which are natural product that are efficient to preventing carcinogenesis. Their are the various medicines available in the marketplace to thrilled the various types of cancer but there is no drug is established to be fully active against cancer.The medicinal, natural drug is used in the cancer is vinca. Vinca is a important medicinal plant which is belong to family of apocynace.They are naturally occurring or semi-synthetic nitrogenous base , extracted from the pink periwinkle plant catharonthus 8roseus G. Pon and have not only hypoglycemic but also cytotoxic effects.In this review summarised herbal drug vinca having anticancer properties.
Keywords: Tumour, Meiosis, Mitosis, Vinca alkaloids, Catharanthine
Cite This Article:
Please cite this article in press Vaishnavi Surve et al., A Review: Overview Of Anti-Cancer Herbal Drug.,Indo Am. J. P. Sci, 2025; 12 (01).
Number of Downloads : 10
References:
1.Koval S, Murane W, Sasser A, Seiner O, Troth J, Courtine J, Messay B, Jiang A, Guerrero C, Kodali A. Cancer and its treatments. Dartmouth Undergrad J Sci. 2020;1(Summer):172–87.
2.Cooper G. The cell: a molecular approach. Sunderland: SinauerAssociates; 2000.
3. Migliore L, Coppedè F. Genetic and environmental factors in cancer and neurodegenerative diseases. Mutat Res. 2002;512(2–3):135–53.
4.Yadav AR, Mohite SK. Cancer-a silent killer: an overview. Asian J Pharm Res. 2020;10(3):213–6.
5. Diori Karidio I.; Sanlier SH. Reviewing cancer’s biology: An eclectic approach. J Egypt Natl Cancer Inst., 2021, 33, 1-7.
6. Kruczynski A, Hill BT. Vinflunine, the latest Vinca alkaloid in clinical development. 2001; 40(2):159-73.
7. Braguer D, Barret JM, McDaid H, Kruczynski A.Antitumor activity of vinflunine: effector pathways And potential for synergies. Semin Oncol, 2008. Doi: 10.1053/ j.seminoncol. 2008.01.011.
8. Ngan VK, Bellman K, Panda D, Hill BT, Jordan MA,Wilson L. Novel actions of the antitumor Drugs vinflunine and vinorelbine on microtubules. Cancer Res.,2000; 60(18):5045-51.
9.Furuse K, Fukuoka M, Asamoto H, Niitani H, Kimura I, Sakuma A et al. A randomized comparative Study of 254-S plus vindesine (VDS) vs. Cisplatin (CDDP) plus VDS in patients with advanced non-small Cell lung cancer (NSCLC). Gan To Kagaku Ryoho. 1992; 19(7):1019-26.
10. Coyle T., Levante S., Shetler M. And Winfield. J., In vitro and in vivo cytotoxicity of gossypol against Central nervous system tumor cell lines, Journal of Neuro Oncology., 1994, 19, 25
11.Gilbert N.E., Reilly J.E., Chang C.J., Lin Y.C. and Brueggemeier R.W., Antiproliferative activity of Gossypol and gossypolone on human breast cancer cells, Life Sciences., 1995 , 57, 61.
12. Zhen H.S., Study of anticancer effect in vivo of active fraction from Nervillia fordii, Zhong, Yao Cai, 2007, 30(9), 1095.
13. Saleem M., Hushum M., Harkonen P., Pihlaja K., Inhibition of cancer cell growth by crude extract And phenolics of Terminalia chebula fruit, Journal of Ethno pharmacology., 2002, 81, 327.
14. Katiyar S.K., Agarwal R. And Mukhtar H., Inhibition of tumor promotion in SENCAR mouse skin by Ethanol extract of Zingiber officinale rhizome, Cancer Research., 1996, 56(5), 1023.
15.Alba Bhutkar MA, Bhise SB. Comparative Studies on Antioxidant Properties of Catharanthus Rosea and Catharanthus. International Journal Of Pharmaceutical Techniques, 2011, 3(3): 1551-1556.
16.Brogan C. Alkaloids cancer treatments. 2010.
17.Asma N., et al. “An updated Review on Catharanthus Roseus:Phytochemical and Pharmacological Analysis”. Indian Research Journal of Pharmacy and Science 3.2 (2016): 631-653.
18. CatharantusRoseus– periwinkle. Tropiclab Inc.www.tropilab.com/periwinkle.htm
19.Yogesh P. “Evaluation of hypolipidemic activity of leaf juice of Catharanthus roseus (Linn.)”. Acta Poloniae Pharmaceutica – Drug Research 68.6 (2011) :927-935.essed 20 July 2008).
20.Wilson L, Panda D, Jordan MA. Modulation of microtubule dynamicsby drugs: a paradigm for the actions of cellular regulators. Cellstructure and function. 1999;24(5):329–335.
21. Hamel E. Interactions of antimitotic peptides and depsipeptides withtubulin. Biopolymers. 2002;66(3):142–60.
22. Dhyani P, Quispe C, Sharma E, Bahukhandi A, Sati P, Attri DC.Anticancer potential of alkaloids: a key emphasis to colchicine,vinblastine, vincristine, vindesine, vinorelbine and vincamine. Cancer Cell Int. 2022;22(1):1–20.
23. Pinard PV, Garès M, Wright M. Differential in vitro association ofvinca alkaloid-induced tubulin spiral filaments into aggregated spirals.Biochem Pharmacologic. 1999;58(6):959–71.
24. Himes RH, Kersey RN, Bettinger IH, Samson FE. Action of the vincaalkaloids vincristine, vinblastine, and desacetyl vinblastine amide onmicrotubules in vitro. Cancer Res. 1976;36(10):3798–802.
25. Singer WD, Himes RH. Cellular uptake and tubulin binding propertiesof four Vinca alkaloids. Biochem Pharmacol. 1992;43(3):545–51.
26. Baguley BC, Holdaway KM, Thomsen LL, Zhuang L, Zwi LJ.Inhibition of growth of colon 38 adenocarcinoma by vinblastine andcolchicine: evidence for a vascular mechanism. Eur J Cancer ClinOncol. 1991;27(4):482–7.
27. Hill BT, Fiebig HH, Waud WR, Poupon MF, Colpaert F, KruczynskiA. Superior in vivo experimental antitumour activity of vinflunine,relative to vinorelbine, in a panel of human tumour xenografts. Eur JCancer. 1999;35(3):512–20.