Volume : 12, Issue : 01, January – 2025
Title:
A REVIEW ARTICLE ON: MOUTH DISSOLVING STRIPS – A NOVEL DRUG DELIVERY SYSTEM
Authors :
Ajay A. Jadhav, Prof. Mr. Harishkumar K. Rathod, Dr. Swati P. Deshmukh
Abstract :
This review article presents the mouth dissolving strips as a novel approach. The mouth dissolving strips are the novel drug delivery system in today’s scenario. It is the most popular and patient friendly method of medicines administration. This system is eminent of among pediatrics and geriatrics. Due to this simplicity, ability to prevent pain, this route is widely used. In this system the drug is swallowed which enters into the systematic circulation and gives desired effect. High stability, easy transportation, pleasant taste, ease of administration are some of its advantages. It is formulation consideration involves active pharmaceutical ingredient, film forming polymers, plasticizers, surfactants, sweetening agents, saliva stimulating agents, flavoring agents, and coloring agents. The method of preparation of mouth dissolving strips involves the solvent casting method, semisolid casting, hot melt extrusion, solid dispersion extrusion and rolling method. The formulation is analyzed through various evaluation parameters. The mouth dissolving strips are evaluated by thickness, dryness test, tensile strength, percent elongation, tear resistance, folding endurance, Young’s modulus, transparency, contact angle, in-vitro disintegration test, in-vitro dissolution studies, swelling property, content uniformity, percentage moisture loss, surface pH test, organoleptic test, permeation studies, stability study parameters. This review article also involves the packaging of mouth dissolving strips Thus, this review article emphasizes on the novel approach of mouth dissolving strips which helps in enhancing bioavailability, onset of action and thus produce a desired therapeutic effect.
Key Words: Solvent casting, hot melt extrusion, solid dispersion extrusion and compliance
Cite This Article:
Please cite this article in press Ajay A. Jadhav et al., A Review Article On: Mouth Dissolving Strips –A Novel Drug Delivery System.,Indo Am. J. P. Sci, 2025; 12 (01).
Number of Downloads : 10
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