Volume : 12, Issue : 02, February – 2025
Title:
DEVELOPMENT AND EVALUATION OF COLON TARGETED MICROSPHERE OF METOPROLOL
Authors :
Patil Akshay Sanjay, Roshani Nayak, Naveen Gupta
Abstract :
Controlled release oral drug delivery systems have been shown to more advantages over conventional systems. These include increased patient compliance, selective pharmacological action; reduced side effect and reduced dosing frequency. These systems may therefore have a significantly beneficial outcome in therapeutic efficacy. The aim of current examination is the improvement and assessment of controlled site-specific drug delivery system at colonic region for Selective β1 receptor blocker of Metoprolol succinate with the objective to prepare the controlled release matrix coated microspheres with varying proportions of polymers to produce better bioavailability for minimize the dose, avoid first pass metabolism of the drug within the gastrointestinal tract and improve the patient compliance.
Keywords: Metoprolol, colon targeted, microsphere, controlled release
Cite This Article:
Please cite this article in press Patil Akshay Sanjay et al., Development And Evaluation Of Colon Targeted Microsphere Of Metoprolol., Indo Am. J. P. Sci, 2025; 12 (02).
Number of Downloads : 10
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