Volume : 12, Issue : 03, March – 2025

Title:

FORMULATION AND EVALUATION OF MELT IN MOUTH SILDENAFIL CITRATE TABLETS BY USING SUPER DISINTEGRANTS
‬

Authors :

Bhavya Paleti*, Kondetti Devi Priya, Kumavath Sravani Bai, Mohammed Ibham shabrooz, Putta Somaiah, Rachamallu Rohitha Sai

Abstract :

New Using the solvent evaporation approach, co-processed super disintegrants were created by integrating one super disintegrant into the particle structure of another. By using the direct compression method with CCS, Kyron T-314, physical blend, and co-processed combination of both super disintegrants in varying ratios, melt-in-mouth tablets with 25 mg of sildenafil citrate each were created. When creating melt-in-mouth tablets, disintegration time is crucial. The pills with the quickest wetting times were found to have the quickest disintegration times. Compared to tablets containing CCS alone, Kyron T-314 alone, and their physical mixes, the tablets containing co-processed super disintegrants disintegrated more quickly.
Key words: Sildenafil citrate, Kyron T-314, Croscarmellose sodium, Disintegrants

Cite This Article:

Please cite this article in press Bhavya Paleti et al., Formulation And Evaluation Of Melt In Mouth Sildenafil Citrate Tablets By Using Super Disintegrants.,Indo Am. J. P. Sci, 2025; 12 (03).

Number of Downloads : 10

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