Volume : 12, Issue : 04, April – 2025
Title:
THE ROLE OF HERBS IN MANAGEMENT OF VIRAL DISEASES
Authors :
Mohammad Ashhar*, Chetan S. Bajare, Pragati Shinde , Dr. Swati P. Deshmukh
Abstract :
Herbal medicine has gained significant attention as a complementary approach to treating viral diseases, particularly in the context of increasing drug resistance and the side effects associated with conventional antiviral medications. Various herbal plants have demonstrated antiviral properties through their phytochemical constituents, such as flavonoids, alkaloids, and terpenoids. The review highlighting their mechanisms of action, efficacy, and traditional uses in managing viral infections like influenza, hepatitis, and COVID-19. The findings suggest that while herbal remedies can provide supportive treatment and enhance immune response, further clinical trials are necessary to establish their efficacy and safety profiles. Integrating these herbal treatments into conventional therapies may offer a holistic approach to viral disease management. Herbal medicine has emerged as a promising avenue for the treatment and management of viral diseases, particularly due to the growing concerns over the side effects of conventional antiviral drugs and the rising incidence of drug-resistant viral strains. Numerous studies have documented the antiviral properties of various herbal plants, which possess bioactive compounds that interfere with viral replication and enhance the host’s immune response. This review highlights several significant herbal plants renowned for their antiviral properties, including Garlic, Zingiber officinale (ginger), Neem (Azadirachta indica) etc.
Keywords- Herbal medicine, antiviral, ginger, Herbal plants, pathogenic virus , hepatitis C virus, host cell, immunodeficiency virus ,Respiratory viruses, Clinical trials, viral diseases, Traditional medicine, Complementary therapy, Natural remedies, Phototherapy, Viral replication, Immune support.
Cite This Article:
Please cite this article in press Mohammad Ashhar et al., The Role Of Herbs In Management Of Viral Diseases., Indo Am. J. P. Sci, 2025; 12(04).
Number of Downloads : 10
References:
1. Kaio Kitazato1, Yifei Wang2, Nobuyuki Kobayashi1, A review on Viral infectious disease and natural products with antiviral activity
2. World Health Organization (WHO). (2020). The Global Impact of Viral Diseases. Retrieved from https://www.who.int/health-topics/viruses.
3. Murray, C. J. L., et al. (2020). Global burden of viral diseases. The Lancet, 395(10236), 103-112. https://doi.org/10.1016/S0140-6736(19)30258-2
4. World Health Organization (WHO). (2020). The Global Impact of Viral Diseases. Retrieved from https://www.who.int/health-topics/viruses.
5. Morens, D. M., & Fauci, A. S. (2013). Emerging infectious diseases: Threats to human health and global stability. PLOS Pathogens, 9(7), e1003467. https://doi.org/10.1371/journal.ppat.1003467.
6. Akram, M., Tahir, I. M., Shah, S. M. A., Mahmood, Z., Altaf, A., Ahmad, K., & Munir, N. (2018). Antiviral potential of medicinal plants against HIV, HSV, influenza, hepatitis, and coxsackievirus: A systematic review. Phytotherapy Research, 32(5), 811-822. https://doi.org/10.1002/ptr.6022
7. Jassim, S. A. A., & Naji, M. A. (2003). Novel antiviral agents: A medicinal plant perspective. Journal of Applied Microbiology, 95(3), 412-427. https://doi.org/10.1046/j.1365-2672.2003.02026.x
8. Li, S., Chen, C., Zhang, H., Guo, H., Wang, H., Wang, L., & Zhang, X. (2005). Identification of natural compounds with antiviral activities against SARS-associated coronavirus. Antiviral Research, 67(1), 18-23. https://doi.org/10.1016/j.antiviral.2005.02.007
9. Nugraha, R. V., Ridwansyah, H., Ghozali, M., Khairani, A. F., & Atik, N. (2020). Traditional herbal medicine candidates as complementary treatments for COVID-19: A review of their mechanisms, pros, and cons. Evidence-Based Complementary and Alternative Medicine, 2020. https://doi.org/10.1155/2020/2560645
10. Wang, Z., Yang, L., Song, J., & Wang, Y. (2019). Bioactive natural products in treatment of COVID-19-like viral infections. Traditional Medicine and Natural Products, 55(5), 1-16. https://doi.org/10.2174/1381612825666191219120905
11. Saxena, S., Pant, N., Jain, D. C., & Bhakuni, R. S. (2014). Antiviral agents from plants and their application in therapeutics. Journal of Ethnopharmacology, 155(1), 1-10. https://doi.org/10.1016/j.jep.2014.06.050
12. Ankri, S., & Mirelman, D. (1999). “Antiviral properties of allicin from garlic.” Microbes and Infection, 1(2), 125-129.This study highlights the antimicrobial effects of allicin, a key compound in garlic, against various pathogens, including viruses, by interfering with microbial metabolism.
13. Lissiman, E., Bhasale, A. L., & Cohen, M. (2014). “Garlic for the common cold.” Cochrane Database of Systematic Reviews, 11. This review explores the antiviral properties of garlic in reducing the duration and severity of common colds caused by rhinoviruses.
14. Chang, J. S., Wang, K. C., Yeh, C. F., Shieh, D. E., & Chiang, L. C. (2013). Fresh ginger (Zingiber officinale) has antiviral activity against human respiratory syncytial virus in human respiratory tract cell lines. Journal of Ethnopharmacology, 145(1), 146-151. Doi:10.1016/j.jep.2012.10.043
15. Islam, M. T., et al. (2020). Ginger (Zingiber officinale) and its phytochemicals: Therapeutic potential in prevention and treatment of viral diseases. Nutrition & Food Science, 51(5), 1267-1281. Doi:10.1108/NFS-05-2020-0175
16. Chang, J. S., et al. (2013). “Fresh ginger (Zingiber officinale) has antiviral activity against human respiratory syncytial virus in human respiratory tract cell lines.” Journal of Ethnopharmacology, 145(1), 146-151.
17. Suntar, I., et al. (2020). “Zingiber officinale (ginger) as a potential antiviral agent in the COVID-19 treatment.” Phytotherapy Research, 34(12), 3137-3147.
18. Mounce, B. C., Cesaro, T., Carrau, L., Vallet, T., & Vignuzzi, M. (2017). Curcumin inhibits Zika and chikungunya virus infection by inhibiting cell binding. Antiviral Research, 142, 148-157. Doi:10.1016/j.antiviral.2017.03.014
19. Praditya, D., Kirchhoff, L., Brüning, J., Rachmawati, H., Steinmann, J., & Steinmann, E. (2019). Anti-infective properties of the golden spice curcumin. Frontiers in Microbiology, 10, 912. Doi:10.3389/fmicb.2019.00912
20. Zakaryan, H., Arabyan, E., Oo, A., & Zandi, K. (2017). Flavonoids: promising natural compounds against viral infections. Archives of Virology, 162(9), 2539-2551. Doi:10.1007/s00705-017-3417.