Volume : 12, Issue : 04, April – 2025

Title:

EXPLORING NOVEL THERAPEUTIC APPROACHES FOR GASTROESOPHAGEAL REFLUX DISEASE (GERD): ADVANCEMENTS IN PHARMACOLOGICAL, ENDOSCOPIC, AND LIFESTYLE INTERVENTIONS

Authors :

Muhammad Fahad Khaliq, Jatindar, Haresh Kumar,Muhammad Mudassar Shoaib, Muhammad Awais Latif, Abida Wali

Abstract :

Background: Doctor treat patients with Gastroesophageal Reflux Disease (GERD) which shows itself through continuous gastrointestinal issues that force stomach contents up towards the esophagus and brings about heartburn and regurgitation. Medical treatments primarily based on acid suppression have shown limited success in treating the symptoms while also failing to treat the biological cause of GERD. Multiple therapeutic gains occurred through recent industrial improvements in endoscopic procedures along with pharmacological therapies and lifestyle interventions.
Aim: The research evaluated the success of innovative GERD treatment methods which involved contemporary pharmaceutical drugs alongside endoscopic approaches and structured life adjustments.
Methods: The research took place at Allied Hospital Faisalabad throughout February 2024 to January 2025. The study enrolled 100 patients who received GERD diagnosis through clinical evaluation and endoscopic assessment. Researchers separated their participants into groups based on their treatment strategy which included either advanced pharmacological medicine or endoscopic procedures against lifestyle adjustment plans. The research obtained data by conducting patient interviews supported with symptom score assessments and six-month follow-up evaluations.
Results: A total of 100 participants received treatment including 35 patients who received advanced pharmacological medicines and 30 patients who received endoscopic therapy while 35 patients followed structured lifestyle programs. Symptomatic improvement occurred in 85% of patients in the pharmacological group combined with 80% in the endoscopic group and 70% in the lifestyle group. Those patients who received treatment combination between pharmacological therapy and lifestyle changes achieved the maximum symptom reduction alongside the lowest recurrence rates. The various treatment methods produced few adverse side effects among patients.
Conclusion: This research demonstrated the rising effectiveness of new medical treatments used to manage GERD. Both advanced pharmacological drugs and endoscopic techniques which maintained minimally invasive characteristics together with lifestyle changes yielded enhanced symptom relief alongside better patient quality of life. The research evidence exemplifies the need for individualized treatment plans for GERD patients.
Keywords: GERD, Gastroesophageal Reflux Disease, Pharmacological Therapy, Endoscopic Intervention, Lifestyle Modification, Allied Hospital Faisalabad.

Cite This Article:

Please cite this article in press Muhammad Fahad Khaliq et al., Exploring Novel Therapeutic Approaches For Gastroesophageal Reflux Disease (Gerd): Advancements In Pharmacological, Endoscopic, And Lifestyle Interventions.,, Indo Am. J. P. Sci, 2025; 12(04).

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