Volume : 12, Issue : 03, March – 2025
Title:
DEVELOPMENT OF NOVEL ANTIBACTERIAL AGENT
Authors :
Shivani S. Awachar, Vinayak A. Katekar, Dr. Swati P. Deshmukh
Abstract :
The rise of antibiotic-resistant bacteria is a critical global health issue, necessitating the development of novel antibacterial agents. Traditional antibiotics have become increasingly ineffective due to resistance mechanisms, such as enzyme production, efflux pumps, and biofilm formation. This has spurred research into new classes of antibacterial compounds and innovative therapeutic strategies. This study focuses on the discovery and development of a novel antibacterial agent targeting multi-drug-resistant (MDR) bacteria. Employing a combination of in silico modeling, biochemical screening, and in vitro and in vivo efficacy assays, we identified a compound with significant antibacterial properties against various MDR pathogens, including MRSA and Pseudomonas aeruginosa. Mechanistic studies suggest that this agent interferes with bacterial cell wall synthesis and exhibits a low propensity for resistance development. Our findings highlight the compound’s potential as a lead candidate for future drug development, promising an effective solution against persistent bacterial infections and reducing the impact of antibiotic resistance.
Keywords: Antibiotic, Biofilm, Pseudomonas aeruginosa
Cite This Article:
Please cite this article in press Shivani S. Awachar et al., Development Of Novel Antibacterial Agent., Indo Am. J. P. Sci, 2025; 12(05).
Number of Downloads : 10
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