Volume : 12, Issue : 08, August- 2025

Title:

HYPONATREMIA IS ASSOCIATED WITH URINARY RETENTION: THE VASOPRESSIN-DEPENDENT AND -INDEPENDENT PATHWAYS

Authors :

FNU Abdul Rehman, Sardar Khizar Hayat, Zeeshan Ahmed, Umair Arshad, Syed Hassan Mohi Ud Din Gillani, Sami Ullah

Abstract :

Background:Hyponatremia, an ordinary electrolyte disorder, has various neurological and systemic appearance. Latest evidence proposed a potential link between hyponatremia and urinary retention, a circumstance that may increase from altered bladder contractility, pair up with micturition reflex, or increased antidiuretic hormone activity.
Objective:To find out the relationship between hyponatremia and urinary retentively, with highlight on vasopressin-dependent and vasopressin-independent mechanisms.
Methods:A partial study was held which involves adult patients acknowledged with hyponatremia (serum sodium <136 mmol/L). Clinical, laboratory, and bladder ultrasound data were composed. Patients were grouped by vasopressin status (measurable via plasma copeptin) to transform pathways. Urinary retentively was defined as post-void residual volume >155 mL.
Results:A total of 185 patients were involved. Urinary retentively was observed in 39% of patients, with increased prevalence in those with raised vasopressin levels. Vasopressin-dependent cases were linked with concentrated urine and low urinary sodium, whereas vasopressin-independent cases highlight signs of impaired bladder contractility without remarkable urine osmolality changes.
Conclusion:Hyponatremia is remarkably linked with urinary retention, with both vasopressin-mediated water retention and non-vasopressin-related bladder dysfunction. Identification of these mechanisms may increase diagnosis and management.
Keywords: Hyponatremia, Bladder, Urinary tract, Urinary retention

Cite This Article:

Please cite this article in press FNU Abdul Rehman et al., Hyponatremia Is Associated With Urinary Retention: The Vasopressin-Dependent And -Independent Pathways., Indo Am. J. P. Sci, 2025; 12(08)..

Number of Downloads : 10

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