Volume : 12, Issue : 08, August- 2025
Title:
DEVELOPMENT AND IN VITRO EVALUATION OF ALOEVERA MOISTURIZING CREAM
Authors :
MD Saleem*, Afiya, A.Shirisha, B.Harshitha, G.Anand Kumar, C.Charan
Abstract :
The present study focuses on the formulation and evaluation of a moisturizing cream incorporating Aloe vera extract, known for its soothing, hydrating, and healing properties. The aim was to develop a safe, stable, and effective herbal cream for topical application to enhance skin hydration and maintain skin health. The cream was prepared using oil-in-water (O/W) emulsion technique with natural and synthetic ingredients such as stearic acid, cetyl alcohol, glycerin, and preservatives. Aloe vera gel was used as the primary active ingredient due to its excellent moisturizing, anti-inflammatory, and antimicrobial properties. The prepared formulation was subjected to various evaluation parameters including pH, viscosity, spreadability, homogeneity, stability, and skin irritation tests. The results indicated that the cream was smooth, non-greasy, stable over time, and had acceptable physicochemical properties. No signs of skin irritation were observed in volunteers during the study period. The moisturizing effect was also satisfactory upon application, indicating its potential use as a natural skincare product. The study concludes that Aloe vera-based moisturizing cream can be a promising herbal formulation for improving skin hydration and overall skin care due to its natural origin and minimal side effects.
Key words: Aloe vera extract, Moisturizing cream, Glycerine, Vitamin E, Spread ability, Stability.
Cite This Article:
Please cite this article in press Md Saleem et al., Development And In Vitro Evaluation Of Aloevera Moisturizing Cream., Indo Am. J. P. Sci, 2025; 12(08).
Number of Downloads : 10
References:
1. B.S., Kalpesh K. Mehta, Anshu Gupta (2016). Dispensing Pharmacy A Practical Manual (p.p. 389-399). Pharma Med Press.
2. Shah RN, Methal BM, A Hand book of Cosmetics Page No.1
3. Myers D, Surfactant Science and Technology, VCH Publishers: 1992, Pp. 209‐247.
4. V.S.Rabade, M.S.Pawar,G.K.Titarmare. (2020). Formulation and Evaluation of Polyherbal Cold Cream. International Journal for Pharmaceutical Research Scholars, 9(1); 25-31.
5. Gupta AK, Ellis CN, Goldfarb MT et al. The role of fish oil in psoriasis. A randomized, double blind, placebo-controlled study to evaluate the effect of fish oil and topical corticosteroid therapy in psoriasis. Int J Dermatol 1990; 29: 591–595.
6. Zepelin HHH-V, Mrowietz U, Färber L et al. Highly purified omega-3-polyunsaturated fatty acids for topical treatment of psoriasis. Results of a double-blind, placebo-controlled multicentre study. Br J Dermatol 1993; 129: 713–717.
7. Hartop PJ, Allenby CF, Prottey C. Comparison of barrier function and lipids in psoriasis and essential fatty acid-deficient rats. Clin Exp Dermatol 1978; 3: 259–267.
8. Kibbe AW. Handbook of Pharmaceutical Excipients, 3rd edn. American Pharmaceutical Association, Pharmaceutical Press, Washington, London, 2000.
9. Barany E, Lindberg M, Lodén M. Unexpected skin barrier influence from nonionic emulsifiers. Int J Pharm 2000; 195: 189–195.
10. Imokawa G, Akasaki S, Hattori M et al. Selective recovery of deranged water-holding properties by stratum corneum lipids. J Invest Dermatol 1986; 87: 758–761.
11. Jamshiya S, “Formulation and Evaluation of Herbal Skin Cream for Wound Healing” (Doctoral dissertation, RVS College of Pharmaceutical Sciences, Coimbatore
12. Rani S, Singh N ,Gautam SP, “Formulation, Evaluation Optimization and Evaluation of Dendricream for wound healing activity of Artemisia Indica” World journal of pharmacy and pharmaceutical sciences, 2016; 5(8):14831497.
13. Esimone CO, Ibezim EC, Chah KF, “Factors affecting wound healing” Journal of Pharma Allied Sciences, 2005; (1):294-299.
14. Avinash G, Priyanka B, “Wound healing potential of Indian medicinal plants” International Journal of Pharmacy Review & Res, 2013; 2:75-87. s