Volume : 12, Issue : 08, August- 2025
Title:
FORMULATION AND EVALUATION OF BUPRENORPHINE BUCCAL TABLETS
Authors :
Ravi Maloth*, Sana, Sindhu Priya, Thaiseem, Srinu, Md.Malik
Abstract :
Buccal tablet of oral formulations of these drugs have been developed to improve their acceptability to patients and thus improve compliance. The focus of present investigation was to improve solubility, bioavailability and to achieved rapid onset action. Buccal tablets of Buprenorphine were prepared by direct compression technique. Four Formulations were formulated using Ethyl cellulose and HPMC as polymers on Swelling index, Disintegration time. In addition, the prepared tablets were also evaluated for weight variation, thickness, moisture absorption, friability, content uniformity, wetting time and drug release studies. Formulation reveals fast dissolution and disintegration rate of optimized Buprenorphine buccal tablets.
Key words: Buprenorphine, Direct compression technique, FTIR studies, Synthetic polymers polymers, Drug release studies.
Cite This Article:
Please cite this article in press Ravi Maloth et al., Formulation And Evaluation Of Buprenorphine Buccal Tablets., Indo Am. J. P. Sci, 2025; 12(08). /p>
Number of Downloads : 10
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