Volume : 12, Issue : 08, August- 2025
Title:
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF RIVASTIGMINE IN PHARMACEUTICAL DOSAGE FORM BY USING UV-VISIBLE SPECTROSCOPY
Authors :
P.T. Nagaraju*, Y.Sai Pravallika, S.Amreen Sulthana,T.Mayuri
Abstract :
A simple, specific, accurate and precise UV spectrophotometric method was developed and validated for the estimation of Rivastigmine in pharmaceutical dosage form. The stock solution was prepared by weighing 100mg of standard Rivastigmine in 1000ml of 0.1M HCl in volumetric flask. The final stock solution was made to produce 1g/μl with water. Further dilution was prepared as per procedure and were scanned at 209nm. The linearity was found in the concentration range of 1-6 μg/ml. the correlation coefficient was 0.9975. The regression equation was found to be Y= 0.0105X +0.2417 Recovery of Rivastigmine was found to be in the range of 98-102%. The method was validated for limit of detection limit of quantification for estimation of Rivastigmine was found to be μg/ml respectively. The Proposed method can be successfully applied for the quantitative determination of Rivastigmine in pharmaceutical dosage form.
Cite This Article:
Please cite this article in press P.T. Nagaraju et al., Analytical Method Development And Validation Of Rivastigmine In Pharmaceutical Dosage Form By Using Uv-Visible Spectroscopy., Indo Am. J. P. Sci, 2025; 12(08).
Number of Downloads : 10
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