Volume : 12, Issue : 10, October – 2025
Title:
FORMULATION AND EVALUATION OF MICROSPHHERES OF NITAZOXANIDE BY IONOTROPIC GELATIN METHOD
Authors :
Maddela Shiva Charan *, M. Mounika, Dr. D. Venkata Ramana.
Abstract :
In the present work, Microspheres of Nitazoxanide using PLGA and Chitosan as polymers were formulated to deliver Nitazoxanide via oral route. The results of this investigation indicate that Ionotropic gelation technique can be successfully employed to fabricate Nitazoxanide microspheres. In this work an effort was made to formulate microsphere of Nitazoxanide by using different polymers. Prepared formulations are evaluated for bulk density, tapped density, precent mucoadhesion, Percent compressibility, hausners ration, percentage yield, size and interaction study by FTIR and in vitro drug release. Formulation which passed all the evaluation parameters was considered as best formulation of Nitazoxanide. The present study conclusively that Nitazoxanide microsphere could be prepared successfully and formulation F3 was shows satisfactory result.
KEYWORDS: Nitazoxanide, PLGA, Chitosan and Microspheres.
Cite This Article:
Please cite this article in press Maddela Shiva Charan et al., Formulation And Evaluation Of Microsphheres Of Nitazoxanide By Ionotropic Gelatin Method , Indo Am. J. P. Sci, 2025; 12(10).
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