Volume : 12, Issue : 11, November – 2025
Title:
FORMULATION AND EVALUATION OF A HERBAL OINTMENT CONTAINING NEEM AND TURMERIC
Authors :
Gopinath Gangadhar Upare*, Patil Tejaswini Shahadeo, Yasmin Azhar patel, Krishna Rithe, Dr. Kavita Kulkarni
Abstract :
In recent years, interest in herbal medicines and their use has grown significantly, even in places with access to modern medical care. medicinal plants are the richest source of plant-derived substances, and plant-derived medicines have recently attracted great interest toward their versatile application bioactive substances utilized in both conventional and alternative medicine.
The goal of this study is to create and assess an ointment made of neem (Azadirachta) Indica) and an extract of turmeric (Curcuma longa). the maceration method was used to prepare the ethanolic extracts.the preparation of the ointment base and the ointment formulation were completed by Using the levigation method to incorporate the extract into the base. Once the formulation was finished, its physicochemical parameters were assessed.Such as hues, scents, pH, consistency, spreadability, extrudability, diffusion study, solubility, and washability.The formulation’s stability under varied temperature conditions was also assessed, and the results indicate that the irritancy, spreadability, and diffusion study remain unchanged. as a result, it might be used as a medium to simply and effectively administer the therapeutic benefits of turmeric and neem.the majority of herbal ointments are composed of plant extract odours found in the plantsmthemselves. Nowadays, ointments are mostly utilised as therapies for a variety of skin conditions,including cellulitis, psoriasis, eczema, and herpes the formulation and assessment of Neem and Turmeric Extract Ointment are the focus of this investigation. Ethanolic extract is made via the maceration process the ointment was prepared using the levigation method, and its characteristics (physical and chemical)—color, the pH value, accessibility, extrudability, distribution analysis, washability, uniformity, and saturation were assessed by adding the extract as the formulation was finished. Additionally, spreadability and irritability are tested at different temperatures.these extracts have the ability to treat a variety of dermatological conditions when added to ointment compositions.this study compiles the current knowledge on the formulation techniques, phytochemical composition, and assessment criteria of herbal ointments containing turmeric and neem.
Cite This Article:
Please cite this article in press Gopinath Gangadhar Upare et al., Formulation And Evaluation Of A Herbal Ointment Containing Neem And Turmeric, Indo Am. J. P. Sci, 2025; 12(11).
REFERENCES:
1. Rajasree P. H, Vishwanad V, Cherian M, Eldhose J, Singh R, Introduction of Antiseptic Polyherbal Ointment, International Journal of Pharmacy and life sciences, 2012:3(10):30-31.
2. Pandey A, Jagtap J. V., Patil A. A., Kuchekar B. S., Anti-bacterial Activity of Herbal Ointment Containing Azadirachta Indica, Journal of Chemical and Pharmaceutical Research, 2010: (3):182-86.
3. Yamini K, Onesimus T, Curcumin of Herbal Antiacne Gel, International Journal of Pharma and Biosciences, 2013:4(2):956-960.
4. Preeti Kumar, Medicinal Properties of Herbal Ointment, International Journal of Pharmaceutical Technology and Sciences, 2018:6(4):1354-1357.
5. Arvinda Nalla, Krishna Mohan Chinnala, Herbal Ointment for Anti-Microbial Activity, World Journal of Pharmaceutical and Medical Research, 2017: 3(7):113-117.
6. Pande G, Verma K, Singh M, Antibacterial Properties of Azadirachta Indica leaves,International Journal of Pharmacy and Pharmaceutical Sciences, 2014:6(2):444-447.
7. Amol V. Pore, Sanjay K. Bais, Ajit G. Chaudhari, Priyanka S. Deokate, Priyanka B. Satpute, Advanced Herbal Drug Technology, International Journal of Pharmacy and Herbal Technology, 2023:1(1):6-16.
8. Debjit Bhowmik, Sampath kumar, Margret Chandira, Turmeric, Herbal and Traditional Medicine, International Journal of Creative Research and Development, 2009:1(2):107-112.
9. Duvoix A, Blasius R, Delhalle S, Schnekenburger M, Henry E, Diederich M, Therapeutic Effects of Curcumin, Journal of Medicinal Plants Research, 2014:2(3):181-190.
10. Jagtap N. S., Khadabadi S. S., Farooqui I. A., Sawarkar H. A., Evaluation of Herbal Wound Healing, International Journal of Pharmacy and Technology Research, 2009:1(4):1104-1108.
11. Sanjay Bais, Amol Pore, Swati Deshmukh, Cosmetic Science, International Journal of Pharmacy and Herbal Technology, 2023:1(3):141-167.
12. Sukanya M. K., Aruna S. R., Antimicrobial Properties of Neem Leaves, International Journal of Pharmacy and Bio Sciences, 2013:4(4):55-64.
13. Sera kim, Seok Chun ko, Yoon Sook kim, Sang keun Ha, Ho Young Park, Determination of Curcuma longa L leaf Extraction, Journal of Food Quality, 2023:8(2):134-139.
14. Shubhangi E. Sawant, Monali D. Tajane, Formulation and Evaluation of Herbal Ointment Containing Neem and Turmeric Extract, Journal of Scientifics and Innovative Research, 2016:5(4):149-150.
15. Maryam Mulla, Sana Attar, Nazneen Nithore, Reeba Parkar, Formulation and Evaluationof Herbal Ointment, International Journal of Creative Research Thoughts, 2022:10(5):200-205.
16. Indrajeet D, Avinash H. Hosmani, Amrit B. Karmarkar, Appasaheb S. Godage, Sharad B. Kadam, Evaluation Test for Herbal Ointment, International Journal of Pharmacy andPharmaceutical Research, 2009:3(1):6-9.
17. Tribhuvan Singh, Shaik Mohammed Salman, Afifa Namreen, Anas Rasheed, Formulation and Evaluation for Herbal Ointment, International Journal of Applied Pharmaceutical Sciences and Research, 2017: 2(4):99-106.
18. Vikhe D. N, Nandal D. H, Rahul Kunkulol, Formulation and Evaluation for Polyherbal Ointments, Research Journal of Science and Technology, 2020:12(2):167-171.
19. Debjit Bhowmik, Chiranjib, K.P. Sampath kumar, Margret Chandira, B. Jayakar, “Turmeric: A herbal and traditional medicine” Scholars Research Library; Archives of Applied Science Research, 2009:1(2):86- 108.
20. D.Indrajeet, Gonjari, Avinash H.Hosmani, Amrit B. Karmarkar, Appasaheb S. Godage, Sharad B. Kadam, Pandurang N.Dhabale, “Formulation and evaluation of situ gelling thermoreversible mucoadhesive gel of fluconazole”, Drug discovery therapeutics, 2009;3(1): 6-9.
21. Rajasree PH, Viswanad V. Formulation and evaluation of antiseptic activity of polyherbal ointment/ Int J Pharm Life Sci. 2012;3(10):2021-2031.
22. Ms.Maryam Mulla. Sana Attar, Ms. Nazneen Nithore, Ms. Reeba
23. Parkar. Formulation and evaluation of herbal ointment containing Neem and Karanj oil, International journal of creative research thoughts (IJCRT); 2022;10(5):200-205.
24. Ashwinder Singh and Vasudeva Rao Avupat, Development and Validation of UVSpectrophotometric method for the Estimation of Curcumin in Standardised Polyherbal Formulations, J Young Pharm, 2017; 9(4):491-495.
25. Dr. Tribhuvan Singh, Syed Imran U1 Haq, Shaik Mohammed Salman, Afifa Namreen, Anas Rasheed, International Journal of Applied Pharmaceutical Sciences and Research 2017;2(4):99-10
26. Chandra Pratap Singh , Pawan KumarMishra and Surya Prakash Gupta. Designand Formulation of Tridax Procumbensbased Polyherbal Cream for Wound Healing Potential. Pharmacia Lettre,2016, 8(12): 15-21.
27. Rupesh Thakur, Nikita Jain, Raghvendra Pathak and Sardul Singh Sandhu. Practice in WoundHealing Stuides of plants. Evidence BasedComplementary and Alternative Medicine 2011.
28. V. Bharathi, B. Varalakashmi , S. Gomathi, et.al.Antibacterial Activity of Tridax procumbence
29. Linn. International Journal of Pharma Sciencesand Research (IJPSR) volume3. No.4 ,April 2012
30. Amita Pandey, Dr. Shalini Tripathi (2014) . Areview on Pharmacognosy , Prephytochemicaland Pharmacological Analysis of TridaxProcumbens Linn.Pharmatutor.ISSN:78-86,2
31. Manimaran S., Nithya and Praveen T.K. (2014). Development and screening oftopical herbal cream formulation for antimicrobial and wound healing activity, International Journal of Biological and Pharmaceutical Research, 2014; 5(5): 383-388.
32. Lokesh Prasad MS, Kalaskar P Gurunath, SB Chandrasekar. Formulation and Evaluation of Herbal Formulations (ointment, cream, gel) Containing Tridax Procumbens and Areca Catachu. Journal of Scientific and Innovation Research.2017;6(3):97-100.
33. Anil Saini and Dr.Pravesh Gupta. Phytochemical studies of the leaves of Tridax Procumbens. International Journal of Research and Analytical Reviews. Volume 5, Issue 3, July- sep 2018
34. R. Amutha, A. Sudha and P. Pandi selvi , Tridax Procumbence (COAT BUTTONS) – A gift of nature : An overview JPS scientific publication ,India. page 193 – 212.12.
35. Chukwuemeka P. Azubuike. Evaluation of the Antibacterial with Methanolic extract of cassiaalata. Asian Journal of Biomedical and Pharmaceutical Sciences, 2(13) 2012,15-19
36. Kokate C.K., Gokhale S.B., Purohit A.P. A textbook of Pharmacognosy , Nirali Praskashan34th edi. Sept 2013, 9.117.