Volume : 13, Issue : 01, January – 2026
Title:
FORMULATION AND EVALUATION OF SILVER NANOPARTICLES USING AQUEOUS EXTRACT OF LANTANA CAMARA FRESH LEAVES
Authors :
Dr. Sudha Bansal*, Ayesha, B. Sridhar Reddy, M. Koojitha, U. Harish
Abstract :
The aim of this study was to investigate the effectiveness of a strategy based on the development of Silver Nanoparticles as an innovative formulation of Lantana camara extract with improved therapeutic efficacy. Lantana camara Silver Nanoparticles were prepared by green synthesis. FTIR studies indicated no interaction between Extract and excipients. Silver nanoparticles were characterized for particle size, zeta potential, entrapment efficiency and surface morphology. In vitro drug release studies were performed in phosphate buffer of pH 7.4 using diffusion technique. The F5 batch had shown maximum entrapment up to 85.55 % and sustained drug release for 8 h. The scanning electron microscopy and zeta potential study showed formation of good Silver nanoparticles dispersion. The stability study showed successful formation of stable silver nanoparticles.
Key words: Lantana camara, silver nanoparticles, Green synthesis technique, FTIR, in-vitro drug release.
Cite This Article:
Please cite this article in press Sudha Bansal et al., Formulation And Evaluation Of Silver Nanoparticles Using Aqueous Extract Of Lantana Camara Fresh Leaves, Indo Am. J. P. Sci, 2026; 13(01).
REFERENCES:
1. Rai M, Yadav A, Gade A. Silver nanoparticles as a new generation of antimicrobials. Biotechnol Adv. 2009;27(1):76–83.
2. Jain PK, Huang X, El-Sayed IH, El-Sayed MA. Noble metals on the nanoscale: optical and photothermal properties and applications in imaging, sensing, biology, and medicine. Acc Chem Res. 2008;41(12):1578–1586.
3. Iravani S. Green synthesis of metal nanoparticles using plants. Green Chem. 2011;13(10):2638–2650.
4. Ahmed S, Ahmad M, Swami BL, Ikram S. Green synthesis of silver nanoparticles using plant extracts and their antimicrobial activities: a review. Saudi J Biol Sci. 2016;23(1):1–11.
5. Bar H, Bhui DK, Sahoo GP, Sarkar P, Pyne S, Misra A. Green synthesis of silver nanoparticles using seed extract of Jatropha curcas. Colloids Surf A Physicochem Eng Asp. 2009;348(1–3):212–216.
6. Ghisalberti EL. Lantana camara L. (Verbenaceae). Fitoterapia. 2000;71(5):467–486.
7. Sharma OP, Sharma S, Pattabhi V, Mahato SB, Sharma PD. A review of the hepatotoxic plant Lantana camara. Crit Rev Toxicol. 2007;37(4):313–352.
8. Sousa EO, Miranda CM, Nobre CB, Boligon AA, Athayde ML, Costa JGM. Phytochemical analysis and antioxidant activities of Lantana camara and Lantana montevidensis extracts. Ind Crops Prod. 2015;70:7–15.
9. Mittal AK, Chisti Y, Banerjee UC. Synthesis of metallic nanoparticles using plant extracts. Biotechnol Adv. 2013;31(2):346–356.
10. Singh P, Kim YJ, Zhang D, Yang DC. Biological synthesis of nanoparticles from plants and microorganisms. Trends Biotechnol. 2016;34(7):588–599.
11. Zhang Q, Li N, Goebl J, Lu Z, Yin Y. A systematic study of the synthesis of silver nanoplates: is citrate a “magic” reagent? J Am Chem Soc. 2011;133:18931–9.
12. Singh A, Singh NB, Hussain I, Singh H, Yadav V, Singh SC (2016) Green synthesis of nano zinc oxide and evaluation of its impact on germination and metabolic activity of Solanum lycopersicum. J Biotechnol 233:84–94
13. Singh A, Singh NB, Hussain I, Singh H, Singh SC (2015) Plant-nanoparticle interaction: an approach to improve agricultural practices and plant productivity. Int J Pharm Sci Invent 4(8):25–40.
14. Hussain I, Singh NB, Singh A, Singh H, Singh SC (2016) Green synthesis of nanoparticles and its potential application. Biotechnol Lett 38(4):545–560.
15. A. Kilungo, L. Powers, N. Arnold, K. Whelan, K. Paterson, D. Young Evaluation of well designs to improve access to safe and clean water in rural Tanzania Int. J. Environ. Health Res., 15 (1) (2018), p. 64.
16. Duman, H.; Eker, F.; Akdaşçi, E.; Witkowska, A.M.; Bechelany, M.; Karav, S. Silver Nanoparticles: A Comprehensive Review of Synthesis Methods and Chemical and Physical Properties. Nanomaterials 2024, 14, 1527.