Volume : 13, Issue : 05, May – 2026
Title:
FORMULATION AND EVALUATION OF MORINGA OLEIFERA BASED TOPICAL ANTISEPTIC GEL
Authors :
Ayush R. Rathod, Nandkishor B Deshmukh, Dr. Swati P. Deshmukh
Abstract :
Topical drug delivery systems play a vital role in the localized treatment of skin infections, wounds, and inflammatory conditions. Herbal formulations are increasingly preferred due to their safety, affordability, and reduced adverse effects compared to synthetic drugs. Moringa oleifera, a widely used medicinal plant, is rich in bioactive compounds such as flavonoids, phenolics, and alkaloids, which exhibit antimicrobial, antioxidant, and anti-inflammatory properties. The present study focuses on the formulation and evaluation of a topical antiseptic gel containing Moringa oleifera extract. The gel was prepared using Carbopol 940 as a gelling agent and evaluated for physicochemical properties such as pH, viscosity, spreadability, and antimicrobial activity. The results demonstrated that the formulation possessed suitable characteristics for topical application and showed significant antimicrobial activity against common pathogens. Thus, the developed formulation can serve as a safe and effective alternative to conventional antiseptic products. Furthermore, the antimicrobial activity of the formulated gel was assessed against selected microbial strains using standard in-vitro methods. The results demonstrated that the gel exhibited satisfactory physicochemical characteristics with pH in the skin-compatible range, appropriate viscosity, and good spreadability. The formulation also showed significant antimicrobial activity, confirming its effectiveness as a topical antiseptic agent.
In conclusion, the developed Moringa oleifera topical gel represents a safe, effective, and economical herbal alternative to conventional antiseptic formulations. Its natural origin, combined with desirable formulation characteristics and therapeutic efficacy, highlights its potential for future pharmaceutical and clinical applications
Cite This Article:
Please cite this article in press Ayush R. Rathod et al., Formulation and evaluation of Moringa oleifera based topical antiseptic gel, Indo Am. J. P. Sci, 2026; 13(05).
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