Volume : 13, Issue : 06, June – 2026

Title:

REVIEW ON PHYTO-CHEMICAL AND PHARMACOLOGICAL ACTIVITIES ON CINNAMALDEHYDE ZEYLANICUM

Authors :

K. Keerthika *, B. Geetha sree , J. Shushritha , K. Shashank, B. Rushitha, Dr.T.Mangialal.

Abstract :

This review paper involves medicinal uses and pharmacological survey of cinnamaldehyde zeylanicum and belonging to family Lauraceae. The plant has been used traditionally in middle east, south east asia as anti-bacterial, anti-diabetic and anti-fungal. One of the well known representatives of this Genus; cinnamomom . It is widely distributed in different parts of the world and long history traditional medicinal uses. The primary phytoconstituents of cinnamon are,cinnamaldehyde ,cinnamic acid, cinnamyl alchohol,eugenol,coumarin,essential oil,flavonoids and polyphenols. its pharmacological activities are,anti-microbial activity,anti imflammatory activity,anti-oxidant activity,anti-diabetic activity,cardio protective activity, neuro protective activity,anti-cancer activity and gastro protective activity.
Key Words: Cinnamon Zeylanicum,Essential Oil,Anti Diabetic,Anti Bacterial.

Cite This Article:

Please cite this article in press Keerthika et al Review On Phyto-Chemical And Pharmacological Activities On Cinnamaldehyde Zeylanicum.., Indo Am. J. P. Sci, 2026; 13(06).

REFERENCES:

1.Jakhetia V, Patel R, Khatri P, Pahuja N, Garg S, Pandey A, Sharma S. Cinnamon: a pharmacological review. J Adv Sci Res. 2010;1(2):19–23,Sciensage
2.Bansode VJ. A review on pharmacological activities of Cinnamomum cassia Blume. Int J Green Pharm. 2012;6(2):102–108.
3.Matan N, Rimkeeree H, Mawson AJ, Chompreeda P, Haruthaithanasan V, Parker M. Antimicrobial activity of cinnamon and clove oils under modified atmosphere conditions. Int J Food Microbiol. 2006;107(2):180–185.
4.Kim SH, Hyun SH, Choung SY. Anti-diabetic effect of cinnamon extract on blood glucose in db/db mice. J Ethnopharmacol. 2006;104(1–2):119–123.Subash Babu P, Prabuseenivasan S, Ignacimuthu S. Cinnamaldehyde improves glucose metabolism and lipid profile in streptozotocin-induced diabetic rats. Phytomedicine. 2007;14(1):15–22.
5.Shidu Yana. Anti-inflammatory activity of Cosmophloeum twig essential oil and its effects on HepG2 cell lines.
6.Das M, Mandal S, Mallick B, Hazra J. Ethnobotany, phytochemical and pharmacological aspects of Cinnamomum zeylanicum Blume. Int Res J Pharm. 2013;4(4):58-63.
7.Kumar S, Kumari R. Pharmacological properties and their medicinal uses of Cinnamomum: A review. J Pharm Pharmacol. 2019;71(12):1735-1761.
8.Jayaprakasha GK, Rao LJM. Chemistry, biogenesis, and biological activities of Cinnamomum zeylanicum. Crit Rev Food Sci Nutr. 2011;51(6):547-562.
9.Guo J, Yan S, Jiang X, Su Z, Zhang F, Xie J, et al. Advances in pharmacological effects and mechanism of action of cinnamaldehyde. Front Pharmacol. 2024;15.
10.Han R, Li X, Gao X, Lv G. Cinnamaldehyde: Pharmacokinetics, anticancer properties and therapeutic potential. Mol Med Rep. 2024;30(3):163.
11.Rao PV, Gan SH. Cinnamon: A multifaceted medicinal plant. Evid Based Complement Alternat Med. 2014.
12.Tabak M, Armon R, Neeman I. Cinnamon extracts’ inhibitory effect on Helicobacter pylori. J Ethnopharmacol. 1999;67(3):269-277.
13.Prabuseenivasan S, Jayakumar M, Ignacimuthu S. In vitro antibacterial activity of some plant essential oils. BMC Complement Altern Med. 2006;6:39.
14.Subash Babu P, Prabuseenivasan S, Ignacimuthu S. Cinnamaldehyde and its antidiabetic activity in experimental animals.
15.Tung YT, Chua MT, Wang SY, Chang ST. Anti-inflammatory activities of essential oils from Cinnamomum species.
16.Singh G, Maurya S, De Lampasona MP, Catalan CAN. Chemical constituents and antimicrobial activity of cinnamon oil.
17.Balijepalli MK, Buru AS, Sakirolla R, Pichika MR. Cinnamomum genus: A review on its biological activities. Int J Pharm Pharm Sci. 2017.
18.Bandara T, Uluwaduge I, Jansz ER. Bioactivity of cinnamon with special emphasis on diabetes mellitus.
19.Gruenwald J, Freder J, Armbruester N. Cinnamon and health.
20.Shahidi F, Ambigaipalan P. Phenolics and polyphenolics in foods and natural health products.
21.Wagner H, Bladt S. Plant Drug Analysis: A Thin Layer Chromatography Atlas. 2nd ed. Springer; 2009.
22.Stahl E. Thin Layer Chromatography: A Laboratory Handbook. Springer; 1969.
23.Harborne JB. Phytochemical Methods. 3rd ed. Chapman & Hall; 1998.
24.Kokate CK, Purohit AP, Gokhale SB. Pharmacognosy. Nirali Prakashan.
25.Trease GE, Evans WC. Trease and Evans Pharmacognosy. 16th ed.
26.Wallis TE. Textbook of Pharmacognosy. 5th ed.
27.Khandelwal KR. Practical Pharmacognosy: Techniques and Experiments.
28Anonymous. The Wealth of India: Raw Materials. CSIR Publication.
29.Evans WC. Pharmacognosy and Phytochemistry of Medicinal Plants.
30.Frontiers Review. Cinnamomum Species: Bridging Phytochemistry Knowledge, Pharmacological Properties and Toxicological Safety for Health Benefits. 2021.
31.European Food Safety Authority. Coumarin in flavourings and other food ingredients with flavouring properties. EFSA Journal. 2008.
32.World Health Organization. WHO Monographs on Selected Medicinal Plants.
33.British Herbal Pharmacopoeia. Monograph on Cinnamomum zeylanicum Bark.
34.Ranasinghe P, Pigera S, Premakumara GAS, Galappaththy P, Constantine GR, Katulanda P. Medicinal properties of true cinnamon (Cinnamomum zeylanicum): A systematic review. BMC Complement Altern Med. 2013;13:275.