Volume : 13, Issue : 06, June – 2026
Title:
HERBAL POTENTIAL OF NERIUM OLEANDER: PHYTOCHEMICAL PROFILE AND PHARMACOLOGICAL SIGNIFICANCE
Authors :
Shilpa Rajendra Khilare*, Ashvini Bankar, Dr. Sagar Muley
Abstract :
Nerium oleander L. (Apocynaceae), commonly known as oleander, is a widely distributed ornamental shrub recognized both for its remarkable therapeutic potential and its pronounced toxicity. Traditionally used in several healing systems, the plant contains a diverse reservoir of bioactive phytochemicals, especially cardenolides, triterpenoids, flavonoids, alkaloids, and phenolic compounds, which collectively contribute to its pharmacological actions. Over the past decades, extensive scientific interest has focused on its antioxidant, antimicrobial, anti-inflammatory, anticancer, cardiotonic, insecticidal, and wound-healing properties. However, the plant’s potent cardiac glycosides, such as oleandrin and neriifolin, impart narrow therapeutic windows and raise safety concerns. This review comprehensively examines the botanical identity, phytochemical profile, ethnomedicinal relevance, and pharmacological significance of N. oleander, while also addressing its toxicological implications. Understanding both the beneficial and hazardous aspects of this plant is essential for advancing safe therapeutic applications, guiding future research, and developing novel formulations that optimize efficacy while mitigating risks.
Keywords: Nerium oleander, Phytochemistry, Pharmacological significance, Herbal toxicity, Cardiac glycosides etc.
Cite This Article:
Please cite this article in press Shilpa Rajendra Khilare et al., Herbal Potential Of Nerium Oleander: Phytochemical Profile And Pharmacological Significance, Indo Am. J. P. Sci, 2026; 13(06).
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