Volume : 13, Issue : 06, June – 2026
Title:
EVOLVING TRENDS IN UROPATHOGEN RESISTANCE: A COMPREHENSIVE REVIEW OF GLOBAL ANTIBIOGRAM PATTERNS AND STEWARDSHIP IMPLICATIONS.
Authors :
Rincy.K.Geevarghese, Fathimathsafa, Mrs.Vineetha.S, Dr.T.Tamilselvan
Abstract :
A significant global threat to public health and clinical management of urinary tract infections (UTIs) is posed by the increasing prevalence of antimicrobial resistance (AMR) in uropathogens [3,11]. This review provides a synthesis of the findings from the recent research studies that were carried out in a variety of geographical regions to evaluate the distribution of common pathogens and the evolving antibiotic susceptibility patterns of these pathogens [1-2,4-10]. Before culture results are available, an antibiogram helps clinicians choose the best antibiotics by providing cumulative data on bacterial susceptibility within a healthcare facility. Additionally, by encouraging sensible antibiotic use and lowering needless exposure to broad-spectrum agents, antibiograms greatly support antimicrobial stewardship initiatives. The epidemiology, pathogenesis, microbiology, risk factors, antimicrobial resistance mechanisms, clinical implications, diagnostic techniques, and treatment approaches of UTIs are all covered in this narrative review[1,2].According to the available research, Escherichia coli is the most common type of bacteria isolated , followed by Klebsiella species [4,5]. Furthermore, there are concerning trends of resistance to commonly prescribed empiric antibiotics such as ciprofloxacin and amoxicillin-clavulanate [1,2,6,7]. The regional variations [8,9], socioeconomic disparities in healthcare [10], and the impact of the COVID-19 pandemic on prescribing habits [11] all contribute to the complexity of these resistance patterns. It is the purpose of this review to highlight the critical role that institutional cumulative antibiograms [12], the implementation of robust antimicrobial stewardship programs [13], and the adoption of rapid diagnostic technologies [14] play in bridging the gap between empirical treatment and clinical efficacy. Finally, in order to maximize patient outcomes and reduce the number of treatment failures, it is necessary to have evidence-based, locally administered therapy that is guided by ongoing surveillance and analysis.[1,11].
Keywords: Antimicrobial resistance, Uropathogens, Antibiogram, Urinary tract infection, Antimicrobial stewardship,Multidisciplinary stewardship,Diagnostic stewardship.
Cite This Article:
Please cite this article in press Rincy.K.Geevarghese et al Evolving Trends In Uropathogen Resistance: A Comprehensive Review Of Global Antibiogram Patterns And Stewardship Implications, Indo Am. J. P. Sci, 2026; 13(06).
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