Volume : 13, Issue : 08, August – 2026
Title:
DESIGN AND DEVELOPMENT OF HERBAL FORMULATIONS FOR THE TREATMENT OF TOPICAL SKIN DISORDERS
Authors :
Swaroopa Rani Gurram, Mandula Sravanthi, Kothoju Maheshwari, Kuchanapally Sangeetha, Kota Sravani, Kuntigorla Saikiran
Abstract :
The present study was carried out to formulate, characterize, and evaluate a topical antibacterial herbal cream using Piper beetle and Ocimum tenuiflorum extracts as major herbal sources. Herbal medicines are increasingly preferred due to their safety, effectiveness, and fewer side effects compared to synthetic drugs. Piper beetle possesses antimicrobial, antioxidant, and anti-inflammatory properties, while Ocimum tenuiflorum is well known for antibacterial, wound-healing, and antioxidant activities. The herbal extracts were incorporated into a cream base prepared using suitable emulsifying agents and excipients. The cream formulation was evaluated for physicochemical parameters such as appearance, pH, viscosity, spread ability, homogeneity, washability, stability, and antibacterial activity. The formulation exhibited satisfactory antibacterial activity against common skin pathogens and showed acceptable physicochemical properties suitable for topical application. The study suggests that the prepared herbal cream can be used as an effective natural antibacterial topical preparation.The formulation and evaluation of a herbal cream containing extracts from Betel leaf (Piper beetle) and Tulsi (Ocimum sanctum) were carried out to explore their potential therapeutic properties in skin care. .The current study’s goal was to create a herbal cream that will moisturize, nourish, lighten, protect, and treat a range of skin conditions.Betel leaf and Tulsi are known for their antimicrobial, anti-inflammatory, and antioxidant properties, whichare beneficialfor treating skin disorders. Products used to enhance one’s appearance are known as herbal cosmetics. Creating a herbal cream that would moisturize, nourish, whiten, and treat a variety of skin conditions was the aim of the study. Among the fundamental ingredients used to produce the cream are Betel Leaf(Piper betel) and Ocimum sanctum (tulsi leaves).
Keywords: Betel leaf, Piper betle, Tulsi, Ocimum sanctum, Herbal cream, Topical formulation, Antibacterial activity, Antioxidant activity, Anti-inflammatory activity, Herbal cosmetics, Skin care, Wound healing.
Cite This Article:
Please cite this article in press Swaroopa Rani G et al., Design And Development Of Herbal Formulations For The Treatment Of Topical Skin Disorders. Indo Am. J. P. Sci, 2026; 13(08).
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Volume : 13, Issue : 08, August – 2026
Title:
EVALUATION OF ANTIHYPERLIPIDEMIC ACTIVITY OF SAPINDUS EMARGINATUS IN RATS
Authors :
Chinthala Jamima*, Dr.R.narasimha Rao, Dr.N. Raghunandhan
Abstract :
Obesity and hyperlipidemia have become major disorders predominantly causing prevailing cardiovascular diseases and ultimately death. The prolonged use of anti-obesity drugs and statins for reducing obesity and blood lipid levels is leading toward adverse effects of kidneys and muscles, specifically rhabdomyolysis. The objective of this study is to evaluate potential of seeds of Sapindus emarginatus against hyperlipidemia. In this model of Hyperlipidemia, 30 adult male wistar rats (200-250gms) were evenly divided into 5 groups in both groups. Group-1 and Group-2 served as untreated and model controls respectively, while Group-3, 4 and 5 were the treatments groups which were simultaneously treated with standard, 100 and 200 mg/kg extract respectively along with High Fat Diet. On last day, blood samples for biochemical parameters, were obtained under inhaled diether anaesthesia. The outcomes of this study were expressed as mean standard error and data were evaluated by using analysis of variance followed by multiple comparisons. Oral administration of 100 mg/ kg and 200mg/kg body weight of Methanolic extract residual fraction of Moringa oleifera. Leaves exhibited a significant reduction (P < 0.01) in serum lipid parameters such as triglycerides, total cholesterol, low density lipoprotein (LDL), very LDL and increase in high density lipoprotein in hyperlipidemic rats when compared with hyperlipidemic control in both models. Our results demonstrated that Methanolic extract fraction of Sesbania grandiflora. Possessed significant antihyperlipidemic activity.
Keywords: Sesbania grandiflora, Cholesterol, LDL, triglycerides and antihyperlipidemic activity.
Cite This Article:
Please cite this article in press Chinthala Jamimaet al., Evaluation of Antihyperlipidemic activity of Sapindus Emarginatus in rats,, Indo Am. J. P. Sci, 2026; 13(08).
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