Volume : 08, Issue : 08, August – 2021

Title:

41.A PROSPECTIVE OBSERVATIONAL STUDY ON APPRAISAL OF INCIDENCE, PREDISPOSING FACTORS AND CLINICAL OUTCOMES IN NEONATAL SEPSIS

Authors :

*G.Siva Bharat, T.Jai Divya, Sreenu Thalla, J.Venkateswara Rao, Madhuri Para, Sandeep Kanneganti, Rama Rao Nadendla

Abstract :

Neonatal sepsis is a most common and frequent cause of morbidity and mortality in neonates. This study was conducted to appraise the incidence, predisposing factors and clinical outcomes of neonatal sepsis. A non experimental prospective cross sectional study was conducted for a period of 6 months in Neonatal Intensive Care Unit and Sick Newborn Care Unit of tertiary care teaching hospital located in Guntur. Study was ethically approved from Institutional ethical committee. A total of 197 neonates with age 0-28 days with clinical sepsis and culture proved sepsis were included into the study. Among 197 neonates, 78.7% with clinical sepsis and 21.3% neonates with culture positive sepsis. 68.5% neonates were diagnosed with early onset neonatal sepsis and 31.5% with late onset neonatal sepsis. Low birth weight (56.3%) was the predominant risk factor for neonatal sepsis and incidence rate was 20.6%. Klebsiella pneumonia (43.9%) was most isolated microorganism. Neonatal septicemia is one of the leading causes of infant morbidity and mortality. Our study found that sepsis was predominantly found in female patients and inpatients whose mode of delivery is vaginal. Most common isolated organism in culture positive cases is Klebsiella pneumonia. EOS is predominantly seen in culture where as LOS in clinical sepsis.
Keywords: sepsis, gasping, EOS, LOS, mortality

Cite This Article:

Please cite this article in press G.Siva Bharat et al, A Prospective Observational Study On Appraisal Of Incidence, Predisposing Factors And Clinical Outcomes In Neonatal Sepsis., Indo Am. J. P. Sci, 2021; 08(8).

Number of Downloads : 10

References:

1. Shashi Gandhi, KP Ranjan, Neelima Ranjan, Neha Sapre, Mahendra Masani. Incidence of neonatal sepsis in tertiary care hospital: an overview. Int. J. Med Sci. Pub Heal. 2013; 2(3); 548-552.
2. Tilahun Tewabe, Seida Mohammed, Yibeltal Tilahun, Birhanie Melaku, Mequanint Fenta, Tsigiereda Dagnaw, Amare Belachew, Ashagre Molla, Habte Belete. Clinical outcome and risk factors of neonatal sepsis among neonates in Felege Hiwot referral Hospital, Bahir Dar, Amhara Regional State, North West Ethiopia 2016: a retrospective chart review. BMC Res Notes, 2017;10; 1-7.
3. Atmaram Pawar, Asawari Raut, Vijay Kalrao, John Jacob, Isha Godha, Ritty Thomas. Etiology and Clinical Outcomes of Neonatal and Pediatric Sepsis. Arch. Pedia. Inf. Dis. 2016; 4(2); 1-6.
4. Mamta Jajoo, Kapil Kapoor, L. K. Garg, Vikas Manchanda1, S. K. Mittal. To Study the Incidence and Risk Factors of Early Onset Neonatal Sepsis in an Out born Neonatal Intensive Care Unit of India. J. Clin. Neona. 2015; 4 (2); 91-95.
5. Jimba Jatsho, Yoriko Nishizawa, Dorji Pelzom, Ragunath Sharma. Clinical and Bacteriological Profile of Neonatal Sepsis: A Prospective Hospital-Based Study. Int. J. Pedia. 2020; 1-9.
6. Preeti. M. Huggi, B Navadagi, Sanjeev. A study of neonatal septicemia in a tertiary care hospital in kalaburagi. J. Evol. Med. Dent. Sci. 2015, 4. 11957-11963.
7. Ginenus Fekadu, Tsega Abera, Tesfa Tekle. Clinical Treatment Outcomes of Neonatal Sepsis in Neonatal Intensive Care Unit of Wollega University Teaching and Referral Hospital, Nekemte Town, Western Ethiopia. Pedia. Ther. 2019, 9 (1); 1-6.
8. Getabelew A, Aman M, Fantaye E, Yeheyis T. Prevalence of Neonatal Sepsis and Associated Factors among Neonates in Neonatal Intensive Care Unit at Selected Governmental Hospitals in Shashemene Town, Oromia Regional State, Ethiopia 2017. Int. J. Pedia. 2018:1-7
9. Vasantha AR, Kutty SN, Joseph Theodore RB. Neonatal sepsis: Aetiological agents and risk factors. J. Aca. Clin. Micro. 2017; 19: 36-41.
10. N. Muthukumaran Mortality profile of neonatal deaths and deaths due to neonatal sepsis in a tertiary care center in southern India: a retrospective study, Int. J. Cont. Pedia. 2018; 5(4):1583-1587.
11. Pavan Kumar DV, Mohan J, Rakesh PS, Prasad J, Joseph L. Bacteriological profile of neonatal sepsis in a secondary care hospital in rural Tamil Nadu, Southern India.”J. Fam. Med. Prim. Care. 2017, 6(4):735-738.