59.Issue 08 august 21 - INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES

Volume : 08, Issue : 08, August – 2021

Title:

59.AN OVERVIEW OF DIAGNOSTIC MODELS OF DEEP VENOUS THROMBOSIS AND PULMONARY EMBOLISM

Authors :

Mohammed Abdelrahman Almasomi , Aljawharah Saud Alotaibi , Faisal Shaddad AlHarbi , Salhah mohammed Sultan Alqarni , Hisham Hamed Alqarehi , Khloud gobran edriss , Ahmad Hassan Almaliki , Samah Abdulah Hatim ,
Hassan Sameer Shalabi

Abstract :

Venous thromboembolism (VTE), comprising deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common and potentially fatal disease. We carried out a narrative review to assess the possibility of the diagnostic tests used for suspected pulmonary embolism, DVT. For clinical purposes, we estimated the range of pretest probabilities over which each test can accurately confirm or exclude pulmonary embolism. Advanced clinical practitioners are regularly faced with ruling out PE in patients who arrive with non-specific symptoms such as dyspnea and pleuritic chest pain, which can be quite mild and hence easily overlooked. PEs can be difficult to diagnose, especially in the elderly, because their symptoms might be confused with those of other, less serious illnesses.

Cite This Article:

Please cite this article in press Mohammed Abdelrahman Almasomi et al, An Overview Of Diagnostic Models Of Deep Venous Thrombosis And Pulmonary Embolism., Indo Am. J. P. Sci, 2021; 08(08).

Number of Downloads : 10

References:

1. Heit JA. The epidemiology of venous thromboembolism in the community. Thromb Vasc Biol.2008;28:370–372.
2. Silverstein M D, Heit J A, Mohr D N. et al. Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. Arch Intern Med.1998;158(6):585–93.
3. Vishal Sekhri, Nimeshkumar Mehta, Naveen Rawat, Stuart G. Lehrman, and Wilbert S. Management of massive and nonmassive pulmonary embolism .Arch Med Sci. 2012 Dec 20; 8(6): 957–969.doi: 10.5114/aoms.2012.32402
4. Torbicki A, van Beek EJR, Charbonnier B, et al. Guidelines on diagnosis and management of acute pulmonary embolism. Task Force on Pulmonary Embolism – European Society of Cardiology. Eur Heart J.2000;21:1301–36.
5. Kasper W, Konstantinides S, Geibel A, et al. Management strategies and determinants of outcome in acute major pulmonary embolism: results of a multicenter registry. J Am Coll Cardiol. 1997;30:1165–71.
6. Seligsohn U, Lubetsky A. Genetic susceptibility to venous thrombosis. N Engl J Med.2001;344(16):1222–31.
7. Crowther M A, Roberts J, Roberts R. et al. Fibrinolytic variables in patients with recurrent venous thrombosis: a prospective cohort study. Thromb Haemost. 2001;85(3):390–4.
8. Altman D, Vergouwe Y, Royston P, Moons K. Prognosis and prognostic research: validating a prognostic model. BMJ 2009;338:b605.
9. 9. Moons KG, Altman DG, Vergouwe Y, Royston P. Prognosis and prognostic research: application and impact of prognostic models in clinical practice BMJ 2009;338:b606.
10. 10. Moons KG, Kengne AP, Grobbee DE, et al. Risk prediction models: II. External validation, model updating, and impact assessment. Heart 2012;98:691-8.
11. 11. Hendriksen JM, Geersing GJ, Moons KG, de Groot JA. Diagnostic and prognostic prediction models. J Thromb Haemost 2013;11:129-41.
12. 12. Altman D, Royston P. What do we mean by validating a prognostic model? Stat Med 2000;19:453-73.
13. 13. Reilly BM, Evans AT. Translating clinical research into clinical practice: impact of using prediction rules to make decisions. Ann Intern Med 2006;144:201-9.
14. Justice AC, Covinsky KE, Berlin JA. Assessing the generalizability of prognostic information. Ann Intern Med 1999;130:515-24.
15. Knottnerus JA. Between iatrotropic stimulus and interiatric referral: the domain of primary care research.J Clin Epidemiol 2002;55:1201-6.
16. Oudega R, Hoes AW, Moons KG. The Wells rule does not adequately rule out deep venous thrombosis in primary care patients. Ann Intern Med 2005;143:100-7.
17. Toll D, Janssen K, Vergouwe Y, Moons K. Validation, updating and impact of clinical prediction rules: a review. J Clin Epidemiol 2008;61:1085-94.
18. Debray TP, Vergouwe Y, Koffijberg H, Nieboer D, Steyerberg EW, Moons KG. A new framework to enhance the interpretation of external validation studies of clinical prediction models. J Clin Epidemiol2015;68:279-89.

19. Moser KM, Fedullo PF, LitteJohn JK, Crawford R. Frequent asymptomatic pulmonary embolism in patients with deep venous thrombosis. JAMA. 1994;271(3):223–225.
20. Heit JA, Silverstein MD, Mohr DN, et al. Predictors of survival after deep vein thrombosis and pulmonary embolism: a population-based, cohort study. Arch Intern Med. 1999;159(5):445–453.
21. Streiff MB, Segal JB, Tamariz LJ, et al. Duration of vitamin K antagonist therapy for venous thromboembolism: a systematic review of the literature. Am J Hematol. 2006;81(9):684–691.
22. Hull RD, Raskob GE, Brant RF, Pineo GF, Valentine KA. Relation between the time to achieve the lower limit of the APTT therapeutic range and recurrent venous thromboembolism during heparin treatment for deep vein thrombosis. Arch Intern Med. 1997;157(22):2562–2568.
23. Segal JB, Eng J, Jenckes MW, et al. Diagnosis and treatment of deep venous thrombosis and pulmonary embolism. Evid Rep Technol Assess (Summ). 2003(68):1–6.
24. Qaseem A, Snow V, Barry P, et al. Current diagnosis of venous thromboembolism in primary care: a clinical practice guideline from the American Academy of Family Physicians and the American College of Physicians. Ann Fam Med. 2007;5(1):57–62.
25. Segal J, Eng J, Tamariz L, Bass E. Review of the evidence on diagnosis of deep venous thrombosis and pulmonary embolism. Ann Fam Med. 2007;5:63–73.
26. Brown MD, Lau J, Nelson RD, Kline JA. Turbidimetric D-dimer test in the diagnosis of pulmonary embolism: a metaanalysis. Clin Chem. 2003;49:1846–1853.
27. Brown MD, Rowe BH, Reeves MJ, Bermingham JM, Goldhaber SZ. The accuracy of the enzyme-linked immunosorbent assay D-dimer test in the diagnosis of pulmonary embolism: a meta-analysis. Ann Emerg Med. 2002;40:133–144.
28. Rathbun SW, Raskob GE, Whitsett TL. Sensitivity and specificity of helical computed tomography in the diagnosis of pulmonary embolism: a systematic review. Ann Intern Med. 2000;132:227–232.
29. Winer-Muram HT, Rydberg J, Johnson MS, et al. Suspected acute pulmonary embolism: evaluation with multi-detector row CT versus digital subtraction pulmonary arteriography. Radiology. 2004;233:806–815.
30. Roy PM, Colombet I, Durieux P, et al. Systematic review and meta-analysis of strategies for the diagnosis of suspected pulmonary embolism. BMJ. 2005;331:259.
31. Quiroz R, Kucher N, Zou KH, et al. Clinical validity of a negative computed tomography scan in patients with suspected pulmonary embolism: a systematic review. JAMA. 2005;293:2012–2017.