Volume : 08, Issue : 12, December – 2021

Title:

21.AN EVALUATION OF KNOWLEDGE, ATTITUDE, AND PRACTICE OF ADVERSE DRUG REACTION REPORTING AMONG PRESCRIBERS AT TERTIARY CARE HOSPITALS

Authors :

Mohammed Mosa Tafyan, Gassem Mauodah Mojammamy, Jubran Hassan Alakhan, Enaam Mohammed Shbily, Abdulaziz Yousef Abdulrahman Alsalamah, Faisal Jarallah Ali Alrasheed, Noufa Ibrahim Hakami, Wafa Alaullah Essa, Ashjan Mohammed Jatem, Zainab Abdu Bhis Hanin, Renad Mehsen Solan

Abstract :

Adverse drug reactions (ADRs) are anxious unintended responses to drugs that occur at a dose usually used by humans. ADR is a significant problem with a considerable concern as it might cause a high rate of hospital admission. However, ADRs could be prevented by identifying, evaluating, and recording such reactions. Therefore, this study aimed to evaluate prescribers’ knowledge, attitude, and practice (KAP) levels at tertiary care hospitals.
Methods: This cross-sectional study was carried out at tertiary care hospitals. The study used a questionnaire to investigate the level of KAP among prescribers. In addition, the demographics, level of knowledge, attitude, and practice of prescribers were investigated.
Results: This study involved 152 participants; only 44.1% were aware of drugs that have been banned due to ADRs, and 53.3% had reported ADRs before. The total KAP was high among only 32.9%. The level of KAP among prescribers was considerably associated with gender (P=0.0001), the previous reporting of ADRs (P=0.011), and the access to the ADR reporting system (P=0.016).
Conclusion: There was a low level of knowledge, attitude, and practice of reporting ADRs among prescribers at a tertiary hospital.
Keywords: ADRs, KAP, Prescribers, drugs

Cite This Article:

Please cite this article in press Mohammed Mosa Tafyan et al, An Evaluation Of Knowledge, Attitude, And Practice Of Adverse Drug Reaction Reporting Among Prescribers At Tertiary Care Hospitals., Indo Am. J. P. Sci, 2021; 08(12).

Number of Downloads : 10

References:

1. World Health Organization. WHO Technical Report No 498; 1972.
2. Li R, Curtain C, Bereznicki L, Zaidi STR. Community pharmacists’ knowledge and perspectives of reporting adverse drug reactions in Australia: a cross-sectional survey. Int J Clin Pharm, 2018;40(4):878–89.
3. Ahmad A, Patel I, Balkrishnan R, Mohanta G, Manna P. An evaluation of knowledge, attitude and practice of Indian pharmacists towards adverse drug reaction reporting: a pilot study. Perspect Clin Res, 2013;4(4):204–410.
4. Desai CK, Iyer G, Panchal J, Shah S, Dikshit R.K. An evaluation of knowledge, attitude, and practice of adverse drug reaction reporting among prescribers at a tertiary care hospital. Perspect Clin Res. 2011;2(4):129.
5. Van Grootheest K, Olsson S, Couper M, de Jong-van den Berg L. Pharmacists’ role in reporting adverse drug reactions in an international perspective. Pharmacoepidemiol Drug Saf, 2004;13:457-464.
6. World Health Organization. Safety of Medicines: A guide to detecting and reporting adverse drug reactions; Why health professionals need to take action. World Health Organization. 2002.
7. Zolezzi M, Parsotam N. Adverse drug reaction reporting in New Zealand: implications for pharmacists. Ther Clin Risk Manag, 2005;1:181-188.
8. Pirmohamed M, James S, Meakin S, Green C, Scott AK, Walley TJ, et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ, 2004;329(7456):15-9.
9. Ramesh M, Pandit J, Parthasarathi G. Adverse drug reactions in a south Indian hospital-their severity and cost involved. Pharmacoepidemiol Drug Saf, 2003;12:687-92.
10. Einarson T.R. Drug-related hospital admissions. Ann Pharmacother, 1993;27(7-8):832-840.
11. Al-Olah YH, Al Thiab KM. Admissions through the emergency department due to drug-related problems. Ann Saudi Med, 2008;28(6):426-429.
12. Pirmohamed M, Breckenridge A, Kitteringham N, Park B. Fortnightly review. Adverse drug reactions. Br Med J, 1998;316:1295–8.
13. Davies EC, Green CF, Taylor S, Williamson PR, Mottram DR, Pirmohamed M. Adverse drug reactions in hospital in-patients: a prospective analysis of 3695 patient-episodes. PLoS ONE, 2009;4:e4439.
14. Mascolo A, Scavone C, Sessa M, di Mauro G, Cimmaruta D, Orlando V, et al. Can causality assessment fulfill the new European definition of adverse drug reaction? A review of methods used in spontaneous reporting. Pharmacolog Res, 2017;123:122-9.
15. World Health Organization. Importance of Pharmacovigilance: Safety Monitoring of Medicinal Products. Geneva, Switzerland: World Health Organization; 2002.
16. Al-Abdulkarim DA, Aljadhey HS, Mahmoud MA, Poff GA, Hassali MA, Ali S. Knowledge and Barriers Among Physicians Toward Adverse Drug Reaction Reporting at a Tertiary Care Hospital in Saudi Arabia. Hospital Pharmacy, 2020:0018578720910385.
17. Nebeker JR, Barach P, Samore MH. Clarifying adverse drug events: a clinician’s guide to terminology, documentation, and reporting. Ann Intern Med, 2004;140:795–801.
18. Jasmine C. Gatti. Editorials: The Importance of Physicians Identifying and Reporting Adverse Drug Events – American Family Physician. Am Fam Physician; 2012:85: 318.
19. Saha L. Role of pharmacovigilance in drug development. Enliven Pharmacovigil Drug Saf, 2014;1(1):9–10.
20. Ponmari SJ, Sivaraman M, Aruna T, Subashree V. Knowledge and awareness of pharmacovigilance among various medical fraternities. Asian J Pharmacol Toxicol, 2015;03(10):45–8.
21. Alomi YA, Alamoudi NH, Alanazi S, Almasoudi AH. Physician’s Practice of Adverse Drug Reaction in Saudi Arabia. Int J Pharmacol Clin Sci, 2021;10(1).
22. Almandil N.B. Healthcare professionals’ awareness and knowledge of adverse drug reactions and pharmacovigilance. Saudi Med J, 2016;37(12):1350-5.
23. The Saudi Food and Drug Authority. The National Pharmacovigilance Centre (NPC). [Updated 2016]. Available from URL: www.sfda.gov.sa.npc
24. Almandil N.B. Healthcare professionals’ awareness and knowledge of adverse drug reactions and pharmacovigilance. Saudi med J, 2016;37(12):1359.
25. Aagaard L, Soendergaard B, Stenver DI, Hansen EH. Knowledge creation about ADRs-turning the perspective from the rear mirror to the projector. Br J Clin Pharmacol, 2008;65:364–76.
26. Saleh HA, Figueras A, Fourrier-Réglat A. Knowledge, attitude and practice of health professionals towards adverse drug reactions reporting. PMR, 2016;3(8):12-21.
27. Pimpalkhute SA, Jaiswal KM, Sontakke SD, Bajait CS, Gaikwad A. Evaluation of awareness about pharmacovigilance and adverse drug reaction monitoring in resident doctors of a tertiary care teaching hospital. Indian J Med Sci, 2012;66:55–61.
28. Palaian S, Ibrahim MI, Mishra P. Health professionals’ knowledge, attitude, and practices towards pharmacovigilance in Nepal. Pharm Pract (Granada), 2011;9:228–35.
29. Al-Hazmi N, Naylor IL. Attitude and awareness of adverse drug reaction reporting by health professionals in seven hospitals in the Holy City of Makkah, Kingdom of Saudi Arabia. J Clin Trials, 2013;3(3):139.
30. Bakhsh TM, Al-Ghamdi MS, Bawazir SA, Omer TY, Qureshi NA. Assessment of hospital physicians’ knowledge, awareness, attitude, and practice of reporting adverse drug reactions in Jeddah, Saudi Arabia. J Adv Med Med Res, 2016:1-6.
31. Hussain SA, Abbas AN, Habeeb SZ, Abd-Ali AK, Abdulrahman ZS. Healthcare personnel’s experience reporting adverse drug reactions in Baghdad city: a cross-sectional study. Int j clin pharm, 2019;41(5):1307-13.
32. Datta S, Sengupta S. An evaluation of knowledge, attitude, and practice of adverse drug reaction reporting in a tertiary care teaching hospital of Sikkim. Perspect clin res, 2015;6(4):200.
33. Tew MM, Teoh BC, Mohd Baidi AS, Saw HL. Assessment of knowledge, attitude, and practices of adverse drug reaction reporting among doctors and pharmacists in primary healthcare. Adv Pharmacoepidemiol Drug Saf, 2016;5(4):1-6.
34. Shah R, Parajuli SB, Pokhrel S. Knowledge of Adverse Drug Reactions Reporting among Doctors and Nurses in a Tertiary Care Hospital: A Descriptive Cross-sectional Study. JNMA, 2021;59(233):22.