Volume : 08, Issue : 02, February – 2021
14.SAFETY AND EFFICACY OF NOVEL CANDIDATE VACCINE AS PROPHYLAXIS FOR CLOSTRIDIUM DIFFICILE
Doaa Osama Suliman Mohammed, Sulafa Saeed Babiker Mahmoud, AMNA AHMED OSMAN MADNI, Susan Abdelrahman Elmahdi Musa, Wefag Ibrahim Elkhider Ahmed
Abstract :
Although substantial research has been conducted on C.difficile Difficult toxoid vaccines are still present in many areas of incoherence in the literature in recent years. Although vaccines have been shown in general to be well tolerated, their efficacy is questionable. In this review, all studies evaluating effectiveness found substantial immune responses after vaccination. However, there is no clear relationship between dose and reaction or between the formulation and reaction of adjuvants. There is also proof that levels of vaccine antibodies may decrease over the long term. These arguments show that further research into the optimal dosage, dosing schedule, and formulation of toxoid vaccines is necessary. Finally, from the surgical endpoints measured during these clinical trials, the vaccines’ efficacy appears promising, but further research is needed to determine their clinical benefits.
Keywords: disease prevention, prophylaxis, toxoid vaccine, vaccination, Clostridium infection, Clostridium difficile
Cite This Article:
Please cite this article in press Doaa Osama Suliman Mohammed et al, Safety And Efficacy Of Novel Candidate Vaccine As Prophylaxis For Clostridium Difficile., Indo Am. J. P. Sci, 2021; 08(02).