Volume : 08, Issue : 01, January – 2021

7. THE RELATIONSHIP OF SERUM LEPTIN LEVELS WITH BLOOD GLUCOSE FASTING IN POLYCYSTIC OVARIAN SYNDROME OF VIRGIN FEMALES

Dr. Maria Aslam, Dr. Anam Aslam, Dr. Zainab Afzal

Abstract :

Objective: The aim of our study was to find out the relationship of serum leptin levels with blood glucose fasting, LH, BMI and FSH in polycystic ovarian syndrome of virgin females.
Study Design: A cross-sectional study.
Place and Duration: The study was conducted at Gynae and Obs department, General Hospital Lahore for the duration of one year starting from November, 2019 to September, 2020.
Methodology: In our present study we collected samples of 77 young virgin females age range from 15 to 30 years. All samples were scrutinized for luteinizing hormone (LH), blood glucose fasting (BGF), serum leptin level and follicle stimulating hormone (FSH). We use Rotterdam Criteria to divide patients in 04 groups. For the measurement of serum leptin assay we use Sandwich- ELISA method. We use a pre-designed questionnaire to gather data from patients. SPSS v.20 was used for the analysis of data.
Results: In our present study we collected samples of 77 young virgin females, out of these 77 samples 14 cases were non- PCOS while 63 cases were PCOS. These patients were divided into 04 sub-groups according to BMI, 14 patients (18.18%) were in lean (non-PCOS) group, 15 patients (19.48%) were in lean (PCOS) group, 30 patients (38.96%) were in overweight (PCOS) group and 18 patients (23.37%) were in obese (PCOS) group respectively.
Conclusion: According to our study we conclude that serum leptin was having positive relationship with blood glucose fasting and BMI in PCOS females. Yet, we couldn’t find any relationship of serum leptin with LH and FSH in PCOS females. In PCOS females the reason for increasing of BSF and BMI is hyperleptinemia.

Keywords :Body Mass Index, Serum Leptin, Polycystic Ovarian Syndrome, Blood Sugar Fasting C

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