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Volume : 08, Issue : 01, January – 2021
145.THE ASSOCIATION OF PLASMA GLUCOSE LEVELS WITH LIPID PROFILE IN TYPE 2 DIABETES MELLITUS
Dr Amjad Hussain, Dr Afeefa Ghafar, Dr Muhammad Ahmad Raza
Abstract :
Objective: The aim of our study was to find out the association of plasma glucose levels with lipid profile in type 2 diabetes mellitus.
Study Design: A case control study.
Place & Duration: This study was conducted at medicine department pf Holy Family Hospital Rawalpindi for the for the duration of one year starting from August, 2019 to July, 2020.
Methodology: In our present study 120 patients were included. We divided the patients into two groups naming; group A and group B. Each group contain 60 patients. In group A type 2 diabetic patients were included and in group B healthy patients with no major illness were included. We analyzed blood samples of participants for glycosylated hemoglobin (HbA1c), lipid profile (Total Cholesterol, Triglycerides, LDL-Cholesterol and HDL-Cholesterol) and fasting plasma glucose (FPG). SPSS v. 20 was used for the analysis of data.
Results: In our present study 120 patients were included. Mean±S.D of FPG in controls were 4.35±0.68 years while mean±S.D in diabetics were 11.23±3.65 years, mean±S.D of HbA1c in controls were 5.31±0.487 years while mean±S.D in diabetics were 6.84±0.482 years. Mean±S.D of Serum total cholesterol in controls were 3.99±1.01 years while mean±S.D in diabetics were 4.68±0.96 years, mean±S.D of triglycerides in controls were 1.56±0.87 years while mean±S.D in diabetics were 2.42±1.22 years and mean±S.D of LDL-Cholesterol in controls were 2.17±0.72 years while mean±S.D in diabetics were 2.46±0.77 years. These parameters were significantly raised in controls. Although mean±S.D of HDL- Cholesterol in controls were 1.21±0.222 years while mean±S.D in diabetics were 1.04±0.224 years. The Body mass index (BMI) were significantly more than the controls.
Conclusion: At the end of our study, we conclude that Total Cholesterol, triglycerides, serum FPG, LDL-cholesterol and HbA1c are significantly increased in Type 2 Diabetic Mellitus while the levels of HDL-cholesterol were decreased in Type 2 Diabetic Mellitus and this is reason for high coronary heart disease incidence in type 2 diabetic mellitus.
Keywords :Type2 Diabetes Mellitus, Total Cholesterol, HDL-Cholesterol, Dyslipidemia, LDL-Cholesterol, Triglycerides
Cite This Article:
Please cite this article in press Amjad Hussain et al, The Association Of Plasma Glucose Levels With Lipid Profile In Type 2 Diabetes Mellitus., Indo Am. J. P. Sci, 2021; 08(1).