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Volume : 08, Issue : 01, January – 2021
157.ANALYZE THE EFFECT ON PRODUCTION AND DEVELOPMENT OF HYPERTENSION OF SEVERE MR ANTAGONISM WITH EPLERENONE
Muhammad Hamza Hafeez, Dr. Nida Rasheed, Muhammad Usama Ali
Abstract :
We examined the impacts of the mineralocorticoid receptor bar in progress with eplerenone on the turn of events and the displacement of hypertension and end organ damage in Dahl rodents with saline touch. Our current research was conducted at Jinnah Hospital, Lahore from March 2019 to February 2020. Eplerenone fundamentally weakened the systolic pulse rate (SBP) reforming elevation (207 ± 4 vs. 178±4 mmHg, p < 0.06), the decrease in proteinuria (603.6 ± 0.06) and the decrease in proteinuria (606.7 ± 0.06). 28.7 vs. 474.8 ± 27.4 mg/24h, p < 0.06), improved scores for lesions of the glomeruli, tubules, renal interstices and vascular system in Dahl, rodents with a salty touch received a high-salt diet. These results show that mineralocorticoid receptor hostility gives assurance to target organs and limits the improvement of elevated circulatory pressure in a saline hypertension model.
Keywords :Production and Development, Hypertension, Severe Mr Antagonism.
Cite This Article:
Please cite this article in press Muhammad Hamza Hafeez et al, Analyze The Effect On Production And Development Of Hypertension Of Severe Mr Antagonism With Eplerenone., Indo Am. J. P. Sci, 2021; 08[1].