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Volume : 08, Issue : 01, January – 2021
178.DIAGNOSTIC ACCURACY OF ULTRASONOGRAPHY IN DIAGNOSIS OF PAPILLARY CARCINOMA IN PATIENTS WITH THYROID NODULES
Zunaira Hannan, Dr Muhammad Talha Nazir, Rao Awais Akhtar
Abstract :
Objective: The objective of this study was to determine the diagnostic accuracy of ultrasonography in the diagnosis of papillary carcinoma in patients with thyroid nodule, keeping histopathology as gold standard.
Material and Methods: This study was a cross sectional study. The study was carried out in Mayo Hospital Lahore and the duration of this study was from January 2019 to January 2020. Sample size was 153, using 59% sensitivity. 69.77% specificity, 95% confidence level, 75% proportion of thyroid nodule, 2.3 and 9% margin of error.
Results: In this study mean age was 49 years with standard deviation ± 2.13. Most of the patients 83% were female and 17% patients were male. Seventy-four percent patients had multinodular and 26% patients had solitary nodules. Correlation of Ultrasonic versus histopathological findings was analyzed as in 55 diagnosed cases of ultrasound, histopathological report has shown 48 cases in which papillary carcinoma was present and in 7 cases the papillary carcinoma not found. Similarly, in 98 undiagnosed cases of ultrasound, histopathological report has shown 82 cases in which papillary carcinoma was present and in 16 cases the papillary carcinoma was not found. Sensitivity was found to be 75%, specificity was 92%, positive predictive value was 87% and negative predicative value was 83%.
Conclusion: In conclusion, CDUS, with the advantages of being noninvasive, radiation free and lower cost, may be employed as the first-line study in screening for PTC. Characteristics of CDUS on thyroid imaging are useful in differentiation of the malignant nodules from the benign ones. However, ultrasound- guided fine needle aspiration of the thyroid nodules should be considered as the standard in diagnosing PTC.
Keywords : Ultrasonic, Histopathological, Papillary Carcinoma, Recurrent Laryngeal Nerve, Papillary Carcinoma Paralysis.
Cite This Article:
Please cite this article in press Zunaira Hannan et al, Diagnostic Accuracy Of Ultrasonography In Diagnosis Of Papillary Carcinoma In Patients With Thyroid Nodules., Indo Am. J. P. Sci, 2021; 08(1).