Volume : 08, Issue : 01, January – 2021
58. THIAZOLIDINONE AS A LEAD COMPOUND IN DRUG DISCOVERY- A REVIEW
Dhanya S*, Prasobh G R, Sheeja Rekha A G, Athira A S, E. Ajila
Thiazolidinones and their derivatives are an important class of compounds in organic and medicinal chemistry. The 4-thiazolidinone ring system is a core structure in various synthetic pharmaceutical agents, displaying a broad spectrum of biological activities such as antitubercular, antibacterial, anti-HIV, anti- inflammatory, antimycobacterial, anticonvulsant, antihistaminic, anticancer and analgesic. This biologically active scaffold has encouraged interest in synthesizing several new compounds by attaching 4- thiazolidinone moieties.
Keywords : Thiazolidinones, Anticancer, Antitubercular.
Cite This Article:
Please cite this article in press Dhanya S et al, Thiazolidinone As A Lead Compound In Drug Discovery- A Review., Indo Am. J. P. Sci, 2021; 08(1).
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