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Volume : 08, Issue : 01, January – 2021


Maryam Shahzadi, Moazza Muzzammil, Amna Mahmood

Abstract :

Introduction: The feature of beta-thalassemia (β-TT) is common in this subcontinent as well as in Pakistan. 3% of our total population has been documented to have β-TT. Iron deficiency anemia (IDA) remains one of the most serious and important eating disorders in the world, especially in Pakistan. Microcytic hypochromic blood pictures are a common symptom of both disorders. The purpose of this study was to see if the two could coexist.
Methods: This was a cross-sectional study conducted at the Department of Internal Medicine of Mayo Hospital Lahore for one-year duration from July 2019 to July 2020. A total of 54 participants were selected from the Medicine department. All of them had β-TT confirmed by capillary hemoglobin electrophoresis. Appropriate advice was given and informed consent was given. Relevant history was collected and a study was conducted. 5 ml of venous blood was collected and sent to the Biochemistry department to measure iron, ferritin, and serum iron binding capacity (TIBC). The transferrin saturation (T.Sat) was calculated from the formula (iron / TIBC) X100.
Results: Finally, 54 patients who met the recruitment criteria were analyzed. Among them, 85% (46) of patients were women and 15% (8) were men. The median age was 30 years (range 11-80 years). Most of the 78% (42) patients belong to the 15 to 44 age group. Mean (± SD) HbA2 (%) was 5.35 (± 1.39), Hb (%) 9.04 ± (1.39), MCV (fl) – 67.02 (± 10.39), MCH (pg) – 21.06 (± 3.99), WFD (%) – 17.77 (± 3.85). Among them, 44.4% (24) had low iron levels (<40 μg / dl), 29.6% (16) had low ferritin (15 μgm / l), 33.3% (18) had high TIBC (> 407 μg / dl), and 50% (27) had low transferrin saturation (<16%). Iron deficiency was found in 13% (7) of patients across all parameters, and 63% (34) of patients were iron deficient in at least one parameter.
Conclusions: In this study, the frequent occurrence of iron deficiency (29.6%) in people with β-TT, which is a potentially correctable clinical condition, was demonstrated. Iron levels among β-TT should be properly assessed, and people with iron deficiency should be treated promptly, which may improve their overall well-being.

Keywords: feature of β-thalassemia, iron deficiency anemia.

Cite This Article:

Please cite this article in press Muhammad Jawad Anwar et al, Extensiveness Of Personality-Reportage Analyzed Cascade And Connected Danger Features Among Pakistani Golden Ager People., Indo Am. J. P. Sci, 2021; 08(1).

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