Volume : 08, Issue : 07, July – 2021

Title:

03.EVALUATION OF DRUG UTILIZATION PATTERN OF HYPOLIPIDEMIC DRUGS AND DRUG RELATED PROBLEMS IN TERTIARY CARE HOSPITAL: PROSPECTIVE STUDY

Authors :

Deepa V Malipatil, Aswin Babu, Gopika Gopal, Sini Sakaria, M G Keshannavar*

Abstract :

Background: Hypolipidaemic drugs are the most commonly prescribed medications for cardiac and neurological disorders.Our study was focused on assessing the risk and benefits of hypolipidameic drugs along with their prescription patterns and their drug related problems.
Methods: An observational prospective study was carried out in 224 patients following the consent of protocol by the Institutional Review Board for evaluating the risk and benefits of hypolipidaemic drugs. Data were scrutinized using open epi version 2 software and WHO core prescribing indicators.
Results: Prescription pattern disclosed that 96.42% patients were advised with atorvastatin and was mostly prescribed for cardiovascular accident (31.25%) cases. On risk assessment based on plasma lipid levels 32.58%,13.39% patients had borderline high and high level of total cholesterol respectively; 51.78%, 6.69% patients had borderline high and high level of triglycerides respectively. 76.69% men and 82.41% women had low HDL cholesterol levels, while 16.07%,7.5% and 1.33% patients had borderline high and very high levels of LDL-C respectively. On benefit assessment based on plasma lipid profile, the mean value of LDL-C after treatment with statins showed a significant decrease in the LDL-C . B ased on the WHO core drug prescribing indicators the mean number of drugs per prescription was 4.2. Drugs prescribed by generic name and from essential drug list was 9.13 and 62.49% respectively. Percentage of encounters with an antibiotic and an injection prescribed was 49.55% and 91.07% respectively.
Conclusion: This study outlines that statins use have shown satisfactory benefit in the reduction LDL-C levels and other cardiovascular diseases. Similar studies ought to be done to enlighten the physicians regarding the advantages on prescribing hypolipidaemic drugs.
Keywords : Drug utilization ,CVD, Hypolipidaemic drugs, dyslipidemia

Cite This Article:

Please cite this article in press M G Keshannavar et al., Evaluation Of Drug Utilization Pattern Of Hypolipidemic Drugs And Drug Related Problems In Tertiary Care Hospital: Prospective Study.., Indo Am. J. P. Sci, 2021; 08(07).

Number of Downloads : 10

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