Volume : 09, Issue : 03, March – 2021

11.COVID-19 INFECTION DURING PREGNANCY: REVIEW ARTICLE

Nagah Mohamad Aboelfetoh, Razan Kamel A Albalawi, Aumniyat Saad A Alrashidi, Ghada Ali R ALanazi, Wesam Kamel Alanazi, Maram Salim S Algrani, Ashwaq Nafie Alanezi

 

Abstract :

Background: Pregnant women and their newborns were also severely affected during this outbreak. Because of physiological changes in the immune and cardiopulmonary processes (such as diaphragm elevation, elevated oxygen consumption, and edema of the respiratory tract mucosa), pregnant women are particularly vulnerable to respiratory pathogens and serious pneumonia.
Aim: To summarize current evidence investigating COVID-19 infection outcomes on mothers and neonates.
Method: This is a systematic review was carried out, including PubMed, Google Scholar, and EBSCO that examining previous studies regarding COVID-19 infection during pregnancy. Authors extracted the data, and then the author’s names, year and region of publication, the study type, period of study, and the result were reported.
Results and Conclusion: The review included 6 studies concluded that; extensive maternal illness, including ICU admission and perinatal mortality during birth, is indicated in existing evidence by COVID‐19 infecting. Conflicting data was obtained regarding mother-fetal infection as many studies with reported positive cases of neonates did not mention restrictions between mother and child during breastfeeding to limit infection.

Cite This Article:

Please cite this article in press Nagah Mohamad Aboelfetoh et al., Covid-19 Infection During Pregnancy: Review Article., Indo Am. J. P. Sci, 2021; 08(03)

Number of Downloads : 10

References:

1. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J. et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med. 2020;382(8):727–733.
2. Wang CL, Liu YY, Wu CH, Wang CY, Wang CH, Long CY. Impact of COVID-19 on Pregnancy. Int J Med Sci. 2021;18(3):763-767. Published 2021 Jan 1. doi:10.7150/ijms.49923
3. Coronavirus disease 2019 (COVID-2019). Situation report 54. World Health Organization; Geneva: 2020. Accessed March 15, 2020..
4. Wang D., Hu B., Hu C. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China [published online ahead of print, Feb. 7, 2020] JAMA. 2020.
5. Yan J., Guo J., Fan C., et al. Coronavirus disease 2019 in pregnant women: a report based on 116 cases. American journal of obstetrics and gynecology. 2020;223(1):111.e1–111.e14. doi: 10.1016/j.ajog.2020.04.014.
6. Zaigham M, Andersson O. Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies. Acta Obstet Gynecol Scand. 2020;99(7):823–829
7. Zhao X., Jiang Y., Zhao Y., Xi H., Liu C., Qu F., Feng X. Analysis of the susceptibility to COVID-19 in pregnancy and recommendations on potential drug screening. Eur. J. Clin. Microbiol. Infect. Dis. 2020;39:1209–1220. doi: 10.1007/s10096-020-03897-6.
8. Benski C, Di Filippo D, Taraschi G, Reich MR. Guidelines for Pregnancy Management During the COVID-19 Pandemic: A Public Health Conundrum. Int J Environ Res Public Health. 2020;17(21):8277. Published 2020 Nov 9. doi:10.3390/ijerph17218277
9. Knight M, Bunch K, Vousden N, et al. Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study. BMJ. 2020;369:m2107. Published 2020 Jun 8. doi:10.1136/bmj.m2107
10. Zaigham M, Andersson O. Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies. Acta Obstet Gynecol Scand. 2020;99(7):823-829. doi:10.1111/aogs.13867
11. Lokken, Erica M et al. “Disease severity, pregnancy outcomes, and maternal deaths among pregnant patients with severe acute respiratory syndrome coronavirus 2 infection in Washington State.” American journal of obstetrics and gynecology, S0002-9378(21)00033-8. 27 Jan. 2021, doi:10.1016/j.ajog.2020.12.1221
12. Abourida Y, Rebahi H, Oussayeh I, et al. Management of Severe COVID-19 in Pregnancy. Case Rep Obstet Gynecol. 2020;2020:8852816. Published 2020 Jul 27. doi:10.1155/2020/8852816
13. Yan J, Guo J, Fan C, et al. Coronavirus disease 2019 in pregnant women: a report based on 116 cases. Am J Obstet Gynecol. 2020;223(1):111.e1-111.e14. doi:10.1016/j.ajog.2020.04.014
14. MELO, Géssyca Cavalcante de and ARAUJO, Karina Conceição Gomes Machado de. COVID-19 infection in pregnant women, preterm delivery, birth weight, and vertical transmission: a systematic review and meta-analysis. Cad. Saúde Pública [online]. 2020, vol.36, n.7 [cited 2021-03-17], e00087320. Available from: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2020000702001&lng=en&nrm=iso>. Epub July 17, 2020. ISSN 1678-4464. https://doi.org/10.1590/0102-311×00087320.
15. Docherty AB, Harrison EM, Green CA, et al. ISARIC4C investigators Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study. BMJ 2020;369:m1985. 10.1136/bmj.m1985.
16. Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19). 28 February 2020.
17. Liu D, Li L, Wu X, Zheng D, Wang J, Yang L. et al. Pregnancy and Perinatal Outcomes of Women With Coronavirus Disease (COVID-19) Pneumonia: A Preliminary Analysis. American Journal of Roentgenology. 2020;18:1–6.
18. Centers for Disease Control and Prevention Data on COVID-19 during pregnancy: severity of maternal illness. 2020. https://www.cdc.gov/coronavirus/2019-ncov/cases-updates/special-populations/pregnancy-data-on-covid-19.html Available at: Accessed Feb. 7, 2021.
19. Guan W.J., Ni Z.Y., Hu Y. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020
20. Wu Z., McGoogan J.M. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA. 2020
21. RCOG. Coronavirus (COVID-19) infection in pregnancy. Information for healthcare professionals. 2020. https://www.rcog.org.uk/globalassets/documents/guidelines/2020-05-13-coronavirus-COVID-19-infection-in-pregnancy.pdf.
22. Liao J., He X., Gong Q., Yang L., Zhou C., Li J. Analysis of vaginal delivery outcomes among pregnant women in Wuhan, China during the COVID-19 pandemic. International Journal of Gynecology & Obstetrics. 2020;150(1):53–57. doi: 10.1002/ijgo.13188.
23. Chen Y., Chen L., Deng Q., et al. The presence of SARS-CoV-2 RNA in the feces of COVID-19 patients. Journal of Medical Virology. 2020;92(7):833–840. doi: 10.1002/jmv.25825.
24. Yu N, Li W, Kang Q, et al. Clinical features and obstetric and neonatal outcomes of pregnant patients with covid-19 in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet Infect Dis 2020;20:559-64. . 10.1016/S1473-3099(20)30176-6
25. Zeng H, Xu C, Fan J, et al. Antibodies in infants born to mothers with covid-19 pneumonia. JAMA 2020. . 10.1001/jama.2020.4861
26. Zeng L, Xia S, Yuan W, et al. Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with covid-19 in Wuhan, China. JAMA Pediatr 2020. . 10.1001/jamapediatrics.2020.0878
27. Dong L, Tian J, He S, et al. Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn. JAMA 2020. . 10.1001/jama.2020.4621
28. Schwartz DA. An analysis of 38 pregnant women with COVID‐19, their newborn infants, and maternal‐fetal transmission of SARS‐CoV‐2: maternal coronavirus infections and pregnancy outcomes. Arch Pathol Lab Med. 2020. doi: 10.5858/arpa.2020‐0901‐SA
29. Zhu H, Wang L, Fang C, et al. Clinical analysis of 10 neonates born to mothers with 2019‐nCoV pneumonia. Transl Pediatr. 2020;9:51‐60.
30. Fan C, Lei D, Fang C, et al. Perinatal transmission of COVID‐19 associated SARS‐CoV‐2: should we worry? Clin Infect Dis. 2020. pii: ciaa226.
31. Ferrazzi E, Frigerio L, Savasi V, Vergani P, Prefumo F, Barresi S, et al. Vaginal delivery in SARS-CoV-2 infected pregnant women in Northern Italy: a retrospective analysis. BJOG 2020;
32. Dotters-Katz SK, Hughes BL. Considerations for obstetric care during the COVID-19 pandemic. Am J Perinatol 2020;