Volume : 08, Issue : 11, November – 2021



Authors :

Ch. Madhavi*, Y. Sreelatha, V. Jhansi Laxmi, Nafees Fatima, Dr.N. Sandeepthi

Abstract :

Floating drug delivery systems (FDDS) are those systems which have a bulk density less than gastric fluids and because of these systems remains buoyant (3-4 hours) for a prolonged peroid of time in the stomach without affecting the gastric emptying rate. Based on the mechanisam of buoyancy, two distinctly different technologies have been utilized in the development of FDDS, which are effervescent system and non – effervescent system.
Keywords: FDDS, buoyant , Gastric emptying rate, ,non – effervescent system.

Cite This Article:

Please cite this article in press Chepuri .Madhavi et al, Formulation And In – Vitro Evaluation Of Floating Hydrogel Beads Of Nimodipine., Indo Am. J. P. Sci, 2021; 08(11).

Number of Downloads : 10


1. Yeole PG, Khan S, Patel VF. Floating drug delivery systems: Need and development. Indian J pharma Sci 2005;67(3):265-72.
2. Timmermans J, Moes AJ. Floating dosages forms: A Review. Int J Pharm1990;62:207-16.
3. Patel MG, Patel RH, Patel M, Patel KJ. Floating drug delivery system: An innovative approach to prolong gastric retention. Available at www.pharmainfo.net.aug.2010.
4. Srivastava AK, Narayanarao D. Floating microspheres of Cimetidine: formulation, characterization and in- vitro evaluation. Acta Pharm 2005;55:277-85.
5. Fursule RA, Patra CN, patil GB, Kosalge SB, patil PO, Deshmukh PK. Study of multiparticulate floating drug delivery system prepared by emulsion gelation technique. Int J Chem Tech Res 2009;1(2):162-7.
6. Jain AK, Jain CP, Tanwar YS, Naruka, PS. Formulation characterization and in vitro evaluation of floating microspheres of Famotidine as a gastro retentive dosage form. Asian J Pharm 2009;3(3):222-6
7. Sanjay K. Jain.,Design and Development of Hydrogel Beads for Targeted Drug Delivery to the Colon, satranidazole. AAPS PharmSciTech 2007; 8 (3)
8. Adhiyaman Rajendran.et.al.,Alginate-Chitosan Particulate System for Sustained Release of Nimodipine, Tropical Journal of Pharmaceutical Research, October 2009; 8 (5): 433-440
9. K.M. Manjanna.et.al.,Formulation and Optimization of Natural Polysaccharide Hydrogel Microbeads of Aceclofenac Sodium for Oral Controlled Drug Delivery, American Journal of Medical Sciences and Medicine, 2013, Vol. 1, No. 1, 5-17.
10. BHATT M. B.et.al.,Formulation And Evaluation Of Ionotropically Gelled Novel Hydrogel Beads Of Valsartan, IJPRBS, 2014; Volume 3(2): 845-859.
11. Payal Deepak.et.al.,Pioglitazone Loaded Chitosan Hydrogel Beads: Fabrication And In-Vitro Characterization, International Journal Of Pharma Professional’s Research Volume-7, Issue-1, January-2016.