18.Issue 10 october 21 - INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES

Volume : 08, Issue : 10, October – 2021

Title:

18.AN OVERVIEW ON PHARMACEUTICAL COCRYSTALS

Authors :

Padala Alekya*, Jagadeesh Panda, D. Komali, S. Neeraja Sukanya

Abstract :

The cocrystal production and properties are intricate in different ways. It exhibits properties corresponding to dissolution rate, melting point, solubility, chemical stability etc. The crystal engineering has been applied to API’s as an implication to pharmaceutical cocrystal which has been increasingly recognized as an attractive option to polymorph, salts, solvates and crystal habit modifications in dosage form design. Pharmaceutical cocrystals formation has been manifested to influence the solid-state properties (solubility and bioavailability) of poorly water-soluble drugs without compromising its pharmacological activity. To date, there is no agreeable definition, what a cocrystal constitutes. This article intended to presents an overview of pharmaceutical cocrystals with different preparation methods, physicochemical properties and analytical characterization methods.
KEY WORDS: cocrystal, API, crystallization, solubility, bioavailability

Cite This Article:

Please cite this article in press Padala Alekya et al, An Overview On Pharmaceutical Cocrystals., Indo Am. J. P. Sci, 2021; 08(10).

Number of Downloads : 10

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