Volume : 08, Issue : 10, October – 2021

Title:

24.ANTIBODY RESPONSE OF COVID-19 VACCINATION IN PREGNANT WOMEN AND TRANS-PLACENTAL PASSAGE INTO CORD BLOOD

Authors :

Dr Sarmad Rafiq, Dr Faizan Rasheed, Dr Arslan Tariq, Dr Saad Abdul Kareem, Dr Rida Ihsan

Abstract :

Introduction: Vaccination against infectious pathogens is one of the most impactful public health interventions, reducing global morbidity and mortality related to infection. Objectives: The main objective of the study is to find the antibody response of COVID-19 vaccination in pregnant women and trans-placental passage into cord blood. Material and methods: This cross-sectional study was conducted in Punjab Health Department during 2020 to 2021. The data was collected from 100 pregnant females who were done with COVID-19 vaccination before giving birth. Results: The data was collected from 100 pregnant females. Three of these women were also infected with SARS-CoV-2 near vaccination; a manual review of their symptoms indicated that they were more likely associated with the infection rather than the vaccine. None of the reports indicated prolonged fever or severe adverse reactions. Conclusion: It is concluded that women, BNT162b2 mRNA vaccination compared with no vaccination was associated with a significantly lower risk of SARS-CoV-2 infection. Interpretation of study findings is limited by the observational design.

Cite This Article:

Please cite this article in press Sarmad Rafiq et al Antibody Response Of Covid-19 Vaccination In Pregnant Women And Trans-Placental Passage Into Cord Blood., Indo Am. J. P. Sci, 2021; 08(10).

Number of Downloads : 10

References:

1. Goldshtein I, Nevo D, Steinberg DM, et al. Association Between BNT162b2 Vaccination and Incidence of SARS-CoV-2 Infection in Pregnant Women. JAMA. 2021;326(8):728–735. doi:10.1001/jama.2021.11035
2. https://www.rcog.org.uk/en/guidelines-research-services/coronavirus-covid-19-pregnancy-and-womens-health/covid-19-vaccines-and-pregnancy/covid-19-vaccines-pregnancy-and-breastfeeding/
3. Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons
4. Gray, K. J., Bordt, E. A., Atyeo, C., Deriso, E., Akinwunmi, B., Young, N., Baez, A. M., Shook, L. L., Cvrk, D., James, K., De Guzman, R. M., Brigida, S., Diouf, K., Goldfarb, I., Bebell, L. M., Yonker, L. M., Fasano, A., Rabi, S. A., Elovitz, M. A., Alter, G., … Edlow, A. G. (2021). COVID-19 vaccine response in pregnant and lactating women: a cohort study. medRxiv : the preprint server for health sciences, 2021.03.07.21253094.
5. Woodworth, K. R., Olsen, E. O., Neelam, V., Lewis, E. L., Galang, R. R., Oduyebo, T., et al. (2020). Birth and Infant Outcomes Following Laboratory-Confirmed SARS-CoV-2 Infection in Pregnancy — SET-NET, 16 Jurisdictions, March 29–October 14, 2020. MMWR Morb. Mortal. Wkly. Rep. 69 (44), 1635–1640. doi: 10.15585/mmwr.mm6944e2
6. Zambrano, L. D., Ellington, S., Strid, P., Galang, R. R., Oduyebo, T., Tong, V. T., et al. (2020). Update: Characteristics of Symptomatic Women of Reproductive Age With Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status – United States, January 22-October 3, 2020. MMWR Morb. Mortal. Wkly. Rep. 69 (44), 1641–1647. doi: 10.15585/mmwr.mm6944e3
7. Yousaf, F., Mubeen, S., Javaid, A., Rafique, M. A., & Ramzan, H. S. (2021). IMPACT OF COVID-19 ON PREGNANCY OUTCOMES: A CROSS SECTIONAL STUDY. International Journal of Medical Science And Diagnosis Research, 5(4). https://doi.org/10.32553/ijmsdr.v5i4.796
8. Khan S, Nabi G, Han G, et al. Novel coronavirus: how the things are in Wuhan. [Published online ahead of print, February 11, 2020.] Clin Microbiol Infect 2020; S1198–743X(20)30084-7. doi:10.1016/j.cmi.2020.02.005