Volume : 09, Issue : 04, April – 2022
Title:
46.PHYTOCHEMICAL SCREENING, IN VITRO ANTI-OXIDANT ACTIVITY AND IN VITRO ANTI-DIABETIC ACTIVITY OF LEAVES OF PAEONIA EMODI EXTRACT
Authors :
Rakesh Kumar Niranjanl,* Dr. Vivek Gupta
Abstract :
Free radicals contribute to more than one hundred disorders in humans. The synthetic antioxidants have been suspected to cause or prompt negative health effects leading to extensive research on naturally occurring antioxidants especially from plant sources. The aim of the present study was to evaluate qualitative and quantitative phytochemical constituents and in vitro antioxidant activities of leaves of Paeonia emodi. Antioxidant activity was carried out by using 1, 1-diphenyl-2-picrylhydrazyl radical (DPPH) assay. The phytochemical screening of leaves of Paeonia emodi revealed the presence of Flavonoid, Phenol, Carbohydrates and Saponins in Hydroalcoholic extract. The percentage yield of Pet. ether and Hydroalcoholic extract of the leaves of Paeonia emodi was found to be 0.756, 2.524% w/w. The total phenolic and flavonoids content of Paeonia emodi leaves of hydroalcoholic extract was found to be 0.965 and 1.214mg/100mg respectively. The results of DPPH scavenging activity for leave ethanolic extract showed IC50 value 82.22, when compared to Ascorbic acid (standard) was 17.68. anti diabetic activity the IC50 values were examined 35.33µg/ml for Acarbose and 279.39µg/ml for Paeonia emodi extract. It indicates the plant has the potency of scavenging free radicals and antidiabetic potential it may provide leads in the ongoing search for natural antioxidants from various medicinal plants to be used in treating diseases related to free radical reactions.
Keywords: Paeonia emodi, Phytochemical Screening, Antioxidant activity, Antidiabetic
Cite This Article:
Please cite this article in press Vivek Gupta et al, Phytochemical Screening, In Vitro Anti-Oxidant Activity And In Vitro Anti-Diabetic Activity Of Leaves Of Paeonia Emodi Extract., Indo Am. J. P. Sci, 2022; 09(04).,
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