Volume : 09, Issue : 04, April – 2022
Title:
55.EVALUATION OF IN-VITRO ANTIHELMINTHIC POTENCY OF ETHANOLIC EXTRACT OF TEPHROSIA PURPUREA
Authors :
Kakunuri Lakshmi *, Adapa Sowmya, Damuluri Haritha, Gokavarapu Anitha,Vaka Krishna Prasad, Amudala Ramya, Bokinala Anusha, Duvvari Vijay Teja
Abstract :
Various species of genus Tephrosia have been extensively studied for their pharmacological activity. Tephrosia purpurea is expected to possess many constituents among them triterpenoids are major constituents. So due to presence of triterpenoids Tephrosia purpurea may possess Antihelmintic activity. In the present work ethanolic extract of leaves of Tephrosia purpurea was evaluated for its Anthelmintics activity against earthworm at three different concentrations (25, 50, 100 mg/ml). The Antihelmintic activity of extract was comparable with Marketed allopathic drugs (Piperazine citrate (10 mg/ml), Albendazole (25 mg/ml, 50 mg/ml), Ivermectin (5 mg/ml), Levamisole (10 mg/ml). 2% v/v Tween 80 in water was taken as a normal control. Marketed allopathic drugs concentrations were prepared using 2% v/v Tween 80. Antihelmintic activity was evaluated by considering the time required for mobility, paralysis and death of worms by all the prepared extracts and marketed allopathic drugs concentrations.
Levamisole>Piperazine citrate>Tephrosia purpurea leaf extract>Ivermectin>Albendazole.
Key Words: Tephrosia purpurea, Antihelmintic activity, Earthworms.
Cite This Article:
Please cite this article in press Kakunuri. Lakshmi et al, Evaluation Of In-Vitro Anti-helminthic Potency Of Ethanolic Extract Of Tephrosia Purpurea., Indo Am. J. P. Sci, 2022; 09(04)..,
Number of Downloads : 10
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