Volume : 09, Issue : 08, August – 2022
Title:
34.FORMULATION, DEVELOPMENT AND EVALUATION OF TRANSDERMAL DRUG DELIVERY SYSTEM OF CIPROFLOXACIN
Authors :
Mausam Kumar Sahu*, Rupesh Kumar Jain, Pushpendra Kumar Khangar, Vivek Jain
Abstract :
In transdermal drug delivery system (TDDS) the drug is mainly delivered through the skin with the aid of transdermal patch which is a medicament adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and to the blood stream. Now a day TDD is a well-accepted means of delivering many drugs to the systemic circulation in order to achieve a desired pharmacological outcome. The current research is to develop ciprofloxacin transdermal patches which may improves drug dissolution, fast absorption, improves the solubilization of lipophilic drugs, prolonged release and enables reduction in dose. The results of the physicochemical characterization of the patches are shown in Table. The thickness ranged between 154 and 179 µm, which showed their uniformity in thickness. Slight changes in weights among the patches was observed with all formulations and ranged from 11.85 mg and 10.34 mg. Drug content ranged from 96.5% to 98.9 %, which indicates good uniformity among all formulations. This result indicates that the process employed to prepare patches in this study was capable of producing patches with uniform drug content and minimal patch variability.
Key words: Ciprofloxacin, Transdermal Patches, Formulation, Evaluation
Cite This Article:
Please cite this article in press Mausam Kumar Sahu et al, Formulation, Development and Evaluation of Transdermal Drug Delivery System of Ciprofloxacin.,Indo Am. J. P. Sci, 2022; 09(8).
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Number of Downloads : 10
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