35.Issue 01 january 22 - INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES

Volume : 09, Issue : 01, January – 2022

Title:

35.A COMPLETE REVIEW ON NANOEMULSION
‬

Authors :

Priyanka Shukla*, Sadhana Singh

Abstract :

Nanoemulsions are colloidal dispersion systems that are thermodynamically stable, composed of two immiscible liquids mixed along with emulsifying agents (surfactants and co-surfactants) to form a single phase. Nanoemulsions have extensively been investigated as drug delivery systems. Nanoemulsions are also clear, transparent. Nanoemulsion are also known as mini-emulsion, ultrafine emulsion, and submicron emulsion. These are the oil-in-water type of emulsions with the average droplet size ranging from 5 nm to 100 nm. Nanoemulsions are thermodynamically stable transparent or translucent dispersions of oil and water stabilized by an interfacial film of surfactant and co-surfactant molecules having a droplet size of less than 100 nm. This review aims to provide consolidated information regarding various formulation and characterization techniques developed for nanoemulsions. Various characterization techniques for nanoemulsion include determination of particle size, photon correlation spectroscopy, differential scanning calorimetry, phase behavior study and transmission electron microscopy etc. Nanoemulsions are further evaluated by studying in vitro drug release, stability, viscosity, refractive index, and pH etc.

Cite This Article:

Please cite this article in press Priyanka Shukla et al, A Complete Review On Nanoemulsion., Indo Am. J. P. Sci, 2022; 09(01).

Number of Downloads : 10

References:

1. Chaudhri Nirvesh, Prajapati S.K., Soni C. Girish; Self nanoemulsion: Advance form of drug delivery system; World journal of pharmacy and pharmaceutical sciences, 2014, vol 3,issue 10, pp. 410-436.
2. Yadav A. Sheela, Singh Dinesh, Poddar SushilKumar; Influence of components of nanoemulsion system for transdermal drug delivery of nimodipine; Asian J Pharm Clin Res, 2012, Vol 5, Issue 3, pp. 209-214.
3. Singh Vishal, Kumar Hari SL; Nanoemulsification: A novel targetted drue delivery tool; Journal of Drug Delivery & Therapeutics , 2012, vol 2, issue 4, pp. 40-45.
4. Kumar Sunil; Role of nanoemulsion in pharmaceutical science- A review; Asian Journal of Research in Pharmaceutical Sciences and Biotechnology, 2014, vol 2,issue 1,pp. 1-15.
5. Oyelaja O. B., Dare E. O., Katare D. P. and Oladoyinbo F. O.; Nanoemulsion: A promising and novel nanotherapeutic vehicle for transdermal drug delivery; International journal of pharmaceutical science and research, 2020; Vol. 11, issue 6, pp. 2636-2648.
6. Bangia Khanna Jyoti, Om Hari; Nanoemulsions : A versatile drug delivery tool; International journal of pharmaceutical science and research, 2015, vol 6, issue 4, pp. 1363-1372.
7. Bhatt Aarti, Bhist Punit, Tyagi Satyanand; Novel drug delivery system-Nanoemulsion: A recent review; Journal of Drug Discovery and Therapeutics, 2013,vol 1; issue 3; pp. 27- 35.
8. Savardekar Pranita , Bajaj Amrita; Nanoemulsion: A review; International journal of research in pharmacy and chemistry, 2016,vol 6, issue 2,pp. 312-322.
9. Thakur Nishi, Garg Garima, Sharma P.K. , Kumar Nitin; Nanoemulsions: A Review on Various Pharmaceutical Application; Global Journal of Pharmacology, 2012, vol 6, issue 3,pp. 222-225.
10. Sharma Navneet; Preparation and Optimization of Nanoemulsions for targeting Drug Delivery; Int. J. Drug Dev. & Res., 2013, vol 5, issue 4,pp. 37-48.
11. Mohammad S Sahid, A Chowdeswari; A review on Nanoemulsion. Scandinavian journal of pharmaceutical science and research, 2014,vol 1,issue 1,pp. 6-9.
12. Mangale M.R. , Pathak S.S., Mor B.A.; anoemulsion: A pharmaceutical overview; Int. J. Pharm. Sci. Rev. Res,2015 , vol 33, issue 1,pp. 244-252.
13. Sharma Surbhi, Sarangdevot Kumkum; Nanoemulsion for cosmetic; IJARPB, 2012, Vol. 2, issue 3, pp. 408-415.
14. Kanwale Nitin P., Dtta Gavali; Nanoemulsion :A new system for drug delivery; World journal of pharmaceutical research,2015, vol 4, issue 11, pp. 310-326.
15. Ajay Thakur, Walia Manpreet Kaur, Kumar Hari SL; Nanoemulsion enhancement of bioavailability of poorly soluble drugs: A review; Pharmacophore , 2013 , vol 4, issue 1, pp. 15- 25.
16. Anthony A. Attama, Charles lovely; Current state of nanoemulsion in drug delivery; Journal of biomaterials and nano-biotechnology, 2011, vol. 2, pp. 626-639.
17. Sokolov Yu.V.; Nanoemulsion as prospective drug delivery system; News of pharmacy, 2014,vol 1, issue 77, pp. 21-25.
18. Jatin Garg, Kumar Praveen; Emerging trends in nanoemulsion design and therapeutics: A review; Asian journal of pharmaceutical sciences and clinical research, 2014, vol. 2, issue 3, pp. 1-16.
19. Bhosale Rajendra Rohit; Nanoemulsion: A Review on Novel Profusion in Advanced Drug Delivery; Indian Journal of Pharmaceutical and Biological Research , 2014,vol 2, issue 1, pp. 122-127.
20. Sharma Nitin, Bansal Mayank; Nanoemulsion: A new concept of delivery system; Chronicles of Young Scientists, 2010, vol 1, issue 2, pp. 2-6.
21. Rajalakshmi R., Mahesh K., Kumar C.K. Ashok; A critical review on nanoemulsion; International Journal of Innovative Drug Discovery,2011, vol 1,issue 1,pp. 1-8.
22. Setya Sonal, Talegaonkar Sushama; Nanoemulsion: Formulation methods and stability aspects; World journal of pharmacy and pharmaceutical sciences, 2014, vol. 3, issue 2, pp. 2214-2228.
23. Joy Jincy, Krishnakumar K, John Anish, Dineshkumar B; Nanoemulsion in pharmaceuticals: A review; Current Research in Drug Targeting ,2015, vol 5, issue1, pp. 1-4.
24. Reddy Kumar ankit B., Debnath Subhashis; Nanoemulsion a novel approach for lipophilic drugs- A review; Asian Journal of pharmaceutical research, 2013 , vol 3,issue 2,pp. 84-92.
25. Selvi P. P.; Formulation and evaluation of aspirin nanoemulsion; Indian Journal of Science, 2016, vol. 23, issue 79, pp. 245-252.
26. Tiwari S. B., Shenoy D.B., Amiji M.M.; Nanoemulsion Formulations for Improved Oral Delivery of Poorly Soluble Drugs; NSTI-Nanotech, 2006, vol 1, issue 1, pp. 475-478.
27. Prajapati T. Shailesh, Pathak Sarjak P, Thakkar Jalaram H, and Patel Chhaganbhai N.; Nanoemulsion based intranasal delivery of risperidone for nose to brain targeting; Bulletin of pharmaceutical research, 2015, vol. 5, issue 1, pp. 6-13.
28. Qidra El K. Raid; A Novel Ophthalmic Pharmaceutical Nano emulsion: Methods of Preparations, Characterizations, and Applications; American journal of pharmatech research, 2015,vol 5, issue 6, pp. 518-537.
29. Kashyap Nagariya, Sharma Kr. Peeyush; Nanoemulsion: Safe ,stable, and effective formulation system for ophthalmology; American journal of pharmatech research, 2013, vol. 3, issue 3, pp. 252-267.
30. Sarker Amit; Nanoemulsion: An excellent mode for delivery of poorly soluble drug through different routes; Journal of Chemical and Pharmaceutical Research, 2015,vol 7, issue 12, pp. 966-976.
31. Sampathi Sunita, Wankar Jitendra; Design, Development and Evaluation of Nanoemulsion and Nanogel of Itraconazole for Transdermal Delivery; Journal of Scientific Research in Pharmacy, 2014,vol 3, issue 1, pp. 6-11.
32. Shakeel Faiyaz; Design, development and evaluation of novel nanoemulsion formulations for transdermal potential of celecoxib; Acta pharm., 2007, vol. 57, pp. 315- 332.
33. Jaiswal Manjit, Sharma P.K.; Nanoemulsion: an advanced mode of drug delivery system. Biotech, 2015, vol 5,pp. 123-127.
34. Sinde P.B.; Component screening of Miconazole nitrate nanoemulsion; Asian journal of biomedical and pharmaceutical sciences, 2013, vol. 3, issue 19, pp. 33-40.
35. Basha Mona; Nanoemulsion as parentral drug delivery system for new anticancer benzimidazole derivative: Formulation and in-vitro evaluation; Egyptian pharmaceutical journal, 2016, vol. 14, pp. 166- 173.
36. Gannu Praveen Kumar, Ajmeera Divya; Nanoemulsion Based Targeting in Cancer Therapeutics; Medicinal chemistry , 2015, vol 5, issue 5,pp. 272-284.
37. Chouksey RK, Pandey H.K., Jain A.K.; Nanoemulsion: A review; Inventil spreading knowledge, 2011, vol 2, issue 1, pp. 982-988.
38. Elmarzugi A. Nagib; Nanoemulsion and Nanoemulgel as a Topical Formulation; IOSR Journal Of Pharmacy,2015, Vol 5,issue 10, pp. 43-47.
39. Gupta Ankur; Nanoemulsions: formation, properties and applications; Royal society of chemistry, 2016, vol 12, issue 11, pp. 1-16.
40. Tamaddon Mohammad Ali; Pharmaceutical Nanoemulsions and Their Potential Topical and Transdermal Applications; Iranian Journal of Pharmaceutical Sciences, 2011,vol 7, issue 3, pp. 139-150.
41. Sukanya G., Mantry Shubhrajit, Anjum Shireen; Review on nanoemulsion; International journal of innovative pharmaceutical sciences and research, 2013 vol. 1, issue 2, pp. 192-205.
42. Mishra Kumar Raj, Soni G.C., Mishra R.P.; Nanoemulsion: A Novel Drug Delivery Tool; International Journal of Pharma Research & Review, 2014,vol 3, issue 7, pp. 32-43.
43. Kumar Harsh; Nanoemulsion: A pharmaceutical review. International journal of pharma professional re22search, 2014,vol 5,issue 2, pp. 1031-1038.
44. Dhas Anuja; Review on nanoemulsion: A novel drug delivery system; European journal of biomedical and pharmaceutical science , 2016, vol 3, issue 4, pp. 156-166.
45. Chime S. A.; Nanoemulsions- Advances in formulation, characterization and applications in drug delivery; Intech, 2014.
46. Shah P.; Nanoemulsion : A pharmaceutical review; Sys Rev Pharm , 2010, vol 1,issue 1, pp.24-32.