Volume : 09, Issue : 07, July – 2022



Authors :

Dr. Bharat .V. Jain, Drx. Kajal Vipin Jain *, Dr. Sandip. R. Pawar, Mr. Tanveer .Y. Shaikh

Abstract :

In-situ Gel for ocular drug delivery is prepares by using mucoadhesive polymers to increase ocular residence time and minimize precorneal drugs loss of given formulation. Ophthalmic in-situ gelling system composed of environmentally sensitive polymers that will be structurally changed in response to small changes in specific condition like Environmental PH, temperature, & ionic strength. In response to environmental changes, installed liquid in-situ rapidly undergoes gelation into the Cul- de-sac of the eye to form visco-elastic gel. This tends to increase ocular residence time and decreases Precorneal drug loss as a result.
KEYWORDS- In-situ Gelling System, Ketorolac Tromethamine, Sodium Alginate, HPMC K4M, Benzalkonium Chloride,

Cite This Article:

Please cite this article in press Bharat .V. Jain et al, To Design, Development And Characterization Of Novel In Situ Gel For Ocular Drug Delivery., Indo Am. J. P. Sci, 2022; 09(7).,

Number of Downloads : 10


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