Volume : 09, Issue : 06, June – 2022



Authors :

Sweety Vishwakarma, Dr. Shailendra Bindaiya, Dr. Shailendra Lariya

Abstract :

Ticagrelor is a P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death. Ticagrelor is used to prevent a serious or life-threatening heart attack or stroke, or death in people who have had a heart attack or who have acute coronary syndrome (ACS; blockage of blood flow to the heart). The objective of this work is to prepare and evaluate fast dissolving sublingual films containing Ticagrelor. Formulation F3 showed the least disintegration time of 8±1sec. Formulations containing only Sodium starch glycolate, Crospovidone and Cross carmellose sodium showed minimum disintegration time of 8±1sec sec select as optimized formulation. The most important criteria of present work are to that dosage form should be dissolved within few seconds. The incorporation of super disintegrating agent to minimizes the disintegrating time.
Key words:Ticagrelor, sublingual films, Formulation, Evaluation

Cite This Article:

Please cite this article in pressSweety Vishwakarmaet al,Formulation And Evaluation Fast Dissolving Sublingual Films Of Ticagrelor.,Indo Am. J. P. Sci, 2022; 09(6).,

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