Volume : 09, Issue : 06, June – 2022
10.IN VITRO ANTIOXIDANT POTENTIAL OF AQUEOUS EXTRACT OF SEEDS OF RICINUS COMMUNIS L
Pratima Mishra*, Dr. Mukesh Dixit, Dr. Kalpana Dave
Plants and plant-based medicaments are the basis of many of the modern pharmaceuticals we use today for our various diseases. The in vitro antioxidant activity of aqueous extract of seeds of Ricinus communis Lwas assessed against DPPH assay method using standard protocols. Phytochemical analysis revealed the presence of alkaloids, flavonoids, phenol, diterpenes and carbohydrates. These studies provided information for standardization and correct identification of this plant material. The diverse array of phytochemicals present in the plant thus suggests its therapeutic potentials which may be explored in drug manufacturing industry as well as in traditional medicine.The aqueous extract showed high antioxidant capacity as proved by their low IC50 concentration. Finally, the results in this study indicate that theexamined plant contain certain amounts of polyphenols and flavonoids, proving them to beperfect sources of antioxidants.
Key words:Ricinus communis, Phytochemical, Antioxidant, DPPH
Cite This Article:
Please cite this article in pressPratima Mishraet al,In Vitro Antioxidant Potential Of Aqueous Extract Of Seeds Of Ricinus Communis L.,Indo Am. J. P. Sci, 2022; 09(6).,
Number of Downloads : 10
1. Cox PA and Balick MJ. 1994. The ethnobotanical approach to drug discovery. Sci Am., 270: 82–87.
2. Etkin NL. 1993. Anthropological methods in Ethnopharmacology. J Ethnopharmacol., 38: 93-104.
3. Rabe T and Van SJ. 1997. Antibacterial activity of South African plants used for medicinal purposes. J. Ethanopharmacol., 56: 810-87.
4. Nishteshvar K and Vidyanath R. 2006. Sahasrayogam – Text with English translation, Chowkhamba Sanskrit Series, Varanasi.
5. Jha, Prabhat; Marcus Flather; Eva Lonn; Michael Farkouh; Salim Yusuf (1995). “The Antioxidant Vitamins and Cardiovascular Disease: A Critical Review of Epidemiologic and Clinical Trial Data. Annals of Internal Medicine 123 (11): 860–872.PMID 7486470.
6. Yu B P, Cellular defenses against damage from reactive oxygen species, Physiol Rev, 74 (1994) 139.
7. Halliwell B &Gutteridge J M C, in Free radicals in biology and medicine, 2nd edition (Clarendon Press, Oxford) 1988, 1.
8. Lata H & Ahuja G K, Role of free radicals in health and disease, Ind J Physio & Allied Sci, 57 (2003) 124.
9. Cotran R S, Kumar V & Collins T, in Robbin’s pathological basis of diseases,6th ed (Thomson Press (I) Ltd, Noida, India) 1999.
10. Kirtikar KR, Basu BD. Indian medicinal plants. 2nd ed. Dehradun: International Book Distributor; 1985. pp. 2274–2277.
11. Yanfg LL, Yen KY, Kiso Y, Kikino H. Antihepatotoxic actions of formosan plant drugs. J Ethanopharmacol. 1987;19:103–110.
12. Visen P, Shukla B, Patnaik G, Tripathi S, Kulshreshtha D, Srimal R, et al. Hepatoprotective activity of Ricinus communis leaves. Int J Pharmacogn. 1992;30:241–250.
13. Shokeen P, Anand P, Krishna YM, Tandon V. Antidiabetic activity of 50% ethanolic extract of Ricinus communis and its purified fractions. Food Chem Toxicol. 2008;46:3458–3466.
14. Capasso F, Mascolo N, Izzo AA, Gaginella TS. Dissociation of castor oil induced diarrhoea and intestinal mucosal injury in rat: effect of NG-nitro-l-arginine methyl ester. Br J Pharmacol. 1994;113:1127–1130.
15. Sandhyakumary K, Bobby RG, Indira M. Antifertility effects of Ricinus communis Linn. on rats. Phytother Res. 2003;17:508–511.