Volume : 09, Issue : 06, June – 2022



Authors :

Jasvinder Saini, Sandeep Kumar, Paras Saini, Manish Panchal, Gopal Thakur, Priyakshi Rana

Abstract :

Chewable tablets are the solid dosage forms which are crushed and Before being ingested, it is chewed between the teeth. chewable tablets are prescribed to them who are not willing to swallow whole tablet or unable to swallow the whole tablet. These pills are formulated to dissolve very easily in oral cavity. Chewable pills have a smooth texture regardless of whether they are chewed or not. dissolution, have a good flavour, and do not leave a harsh or disagreeable aftertaste. Patients in the geriatric and paediatric age groups and patients on the go who may not have simple access to water are in desperate need of an easy-to-swallow dosage Chewable pills are one example. To fulfil the basic needs for the the chewable tablet flavouring agent is added.there are some factors which are involved in the formulation of chewable tablet these are as follows. Flow, lubrication, disintegration, organoleptic qualities, compressibility, compatibility, and stability. A formulator can be apply one or more than one method to get the best result for the formulation with good taste , smooth texture, acceptable compressibility and stability.

Cite This Article:

Please cite this article in press Jasvinder Saini et al, Formulation And Evaluation Of Chewable Tablet: A Review., Indo Am. J. P. Sci, 2022; 09(6).,

Number of Downloads : 10


1. Homayun B, Lin X, Choi HJ. Challenges and recent progress in oral drug delivery systems for biopharmaceuticals. Pharmaceutics 2019; 11:1-29.
2. Liu F, Ranmal S, Batchelor HK, Orlu-Gul M, Ernest TB, Thomas IW, et al. Patient-centred pharmaceutical design to improve acceptability of medicines: Similarities and differences in paediatric and geriatric populations. Drugs 2014; 74:1871-89.
3. Lau ET, Steadman KJ, Cichero JA, Nissen LM. Dosage form modification and oral drug delivery in older people. Adv Drug Deliv Rev 2018;135:75-84.
4. Arvedson JC. Assessment of pediatric dysphagia and feeding disorders: Clinical and instrumental approaches. Dev Disabil Res Rev 2008;14:118-27.
5. Kida IA, Astrøm AN, Strand GV, Masalu JR. Chewing problems and dissatisfaction with chewing ability: A survey of older Tanzanians. Eur J Oral Sci 2007;115:265-74.
6. Kelly J, D’Cruz G, Wright D. Patients with dysphagia: Experiences of taking medication. J Adv Nurs 2010;66:82-91.
7. Nature’s Health, Animal Parade Kids Immune Booster, https://naturesplus.com/products/productdetail.php?productNumber=29978, accessed April 14, 2020.
8. Summary of Product Characteristics. Fosrenol 1000 mg chewable tablets, www.medicines.org.uk/emc/product/7494/smpc#, accessed April 14, 2020.
9. Lachman L, Liberman HA, Kanig LJ. Theory and Practice of Industrial Pharmacy, Vargese Publication House, 3rd Edition, 1990, 293-336.
10. Donald, I.W., Hand book of pharmaceuticals controlled release technology. 1st ed. 2005: Marcel Dekker.
11. Lachmann L, Liberman HA, Schwartz JB. Pharmaceutical Dosage Forms. New York: Marcel Dekker Inc, 1989, 2(1).
12. Udaykumar M, Nageswarao ABN, Kumar VTVS, Giri VV. Fast Dissolving Tablets: New Fangled Drug Delivery System, A Comprehensive Review. International Journal of Research in Drug Delivery. 2012; 2(3):15-18.
13. Patel Y, Shukla A, Saini V, Shrimal N, Sharma P. Chewing Gum as a drug delivery system. International Journal of Pharmaceutical Sciences and Research. 2011; 2:748- 57.
14. Lachman L, Liberman HA, Kanig LJ. Theory and Practice of Industrial Pharmacy, Vargese Publication House, 3rd Edition, 1990, 293-336.
15. Donald, I.W., Hand book of pharmaceuticals controlled release technology. 1st ed. 2005: Marcel Dekker .
16. Parik.M, Handbook of Pharmaceutical Granulation Technology (Drugs and the Pharmaceutical Sciences, ed. Dilip. Vol. 81. 2009.
17. Nanda AR, Garg KS. An update on taste masking technologies for Oral pharmaceuticals. Indian journal Pharma. sci. 2002; 64(1).
18. Roche. Roto-granulations and taste masking coatings for preparation of chewable pharmaceutical tablets. US Patent 5 260 072 9 November, 1993.
19. Khar RK, Sohi H. Taste masking technologies in oral pharmaceuticals: Recent development and approaches. Drug. Dev. Ind. Pharma 2004: 30:429,448.
20. Patel H, Shah V, Upadhyay U. New pharmaceutical excipients in solid dosage forms. International Journal of pharmacy and life sciences. 2011, 2(8).
21. Orally Disintegrating Tablet and film technologies. Second edition, 2004, 177.
22. Solanki HK, Bosuri T, Thakkar JH, Patel CA. Recent Advances in granulation technology. International Journal of Pharmaceutical Sciences Review and Research. 2010; 5(3):48-49.
23. Surbhi G, Seema S, Singh G, Rana AC. Industrial Process Validation of Tablet Dosage Form: An Overview. International Research Journal of Pharmacy. 2012; 3(3):49-51.
24. Ray C, Arora V, Sharma V. Fast dissolving tablets-A Novel drug delivery system for pediatric and geriatric patient. International bulletin of drug research, 1(2), 55- 70.
25. Kathiresan K, Vijin P, Moorthi C, Manavalan R. Formulation and Evaluation of loratadine chewable tablets. Research Journal of pharmaceutical, Biological and chemical sciences. 2010; 1(4):765.