Volume : 09, Issue : 06, June – 2022

Title:

42.SEASONAL INFLUENZA: KNOWLEDGE, ATTITUDE AND VACCINE UPTAKE AMONG ADULT VISITORS OF PRIMARY HEALTHCARE CENTERS, TAIF, SAUDI ARABIA
‬

Authors :

Hatim Mohsen Alkhudaydi, Saeed Alzahrani

Abstract :

Background: Seasonal Influenza vaccination is the suitable tool to reduce the risk of hospitalization and death from complications of influenza in vulnerable patients (patients with chronic diseases, elderly, pregnant women and children). Objectives: To explore the knowledge and attitude about influenza virus and its vaccine as well as to estimate the uptake status of seasonal influenza vaccination and its determinants among adult patients. Patients and methods: A cross sectional design was implemented in Taif city, Western Saudi Arabia among a random sample of adult patients aged between 18 and 65 years attended the primary health care centers affiliated to Ministry of health. A self administered structured validated questionnaire was used for collecting data. Results: A total of 340 adult patients were included in the study. More than half of them (53.5%) were females. Their age ranged between 18 and 65 years with an arithmetic mean of 40.2 years and standard deviation of 13.3 years. Vast majority (99.1%) of the participants were aware about vaccination. The most frequently reported sources of awareness about vaccination were healthcare professionals (22.8%), and family/relatives/friends (18.4%). The total knowledge score ranged between 4 and 12, out of a maximum possible of 13. The median and (IQR) were 8 (8-9). Younger (p=0.007), higher educated (p=0.001), divorced participants (p=0.006), those had their information about vaccination from the community (p=0.037) and participants without history of chronic health problems (p=0.009) were more knowledgeable. The total attitude score ranged between 0 and 8, out of a maximum possible of 10. The median and (IQR) were 3 (2-5). Saudi participants (p=0.019), higher educated (p<0.001), participants who had their information about vaccination from the healthcare professionals (p<0.001) and non smokers (p<0.001) were more likely to express positive attitude towards influenza and its vaccine compared to others. History of receiving a vaccination against influenza in the last season was mentioned by 37.4% of the participants. Females were at lower significant probability of not receiving the vaccine compared to males (Adjusted odds ratio “AOR”=0.35; 95% confidence interval “CI: 0.25-0.81, p=0.008). Compared to primary school educated participants, those with Diploma or Bachelor degrees were at higher risk for not receiving the vaccine (AOR=14.77; 95% “CI: 2.39-91.45, p=0.004 and AOR=3.46; 95% CI: 1.28-9.38, 0.014, respectively). Compared to singles, divorced participants were less likely to not receive the vaccine (AOR=0.23; 95% “CI: 0.09-0.58, p=0.002). Participants with higher knowledge or attitude scores were less likely to not receive the vaccine (AOR=0.64; 95% “CI: 0.56-0.75, p<0.001 and AOR=0.060, 95% CI: 0.49-0.75, p<0.001, respectively). Conclusion: Uptaking of vaccination against influenza in the last season was far below the recommended rate. However, participants with higher knowledge or attitude were more likely to receive the vaccine than their counterparts.
Keywords: Seasonal influenza, Vaccine, Knowledge, Attitude, Uptake

Cite This Article:

Please cite this article in press Hatim Mohsen Alkhudaydi et al, Seasonal Influenza: Knowledge, Attitude And Vaccine Uptake Among Adult Visitors Of Primary Healthcare Centers, Taif, Saudi Arabia., Indo Am. J. P. Sci, 2022; 09(6).,

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References:

1. World Health Organization. World Health Organization (WHO) influenza (seasonal) factsheet N211. Available online: http://www.who.int/mediacentre/factsheets/fs211/en/print.html (accessed on 4 March 2015).
2. WHO. Influenza (Seasonal). WHO [Internet]. 2017 [cited 2017 Nov 14]; Available from: http://www.who.int/ mediacentre/ factsheets /fs211/en/
3. El Khoury G, Salameh P. Influenza vaccination: A cross sectional survey of knowledge, attitude and practices among the Lebanese adult population. Int J Environ Res Public Health. 2015 Dec 5;12(12):15486-97. doi: 10.3390/ijerph121215000.
4. Wang I, Lin C, Chang Y, Lin P, Liang C, Liu Y,et al. Effectiveness of influenza vaccination in elderly diabetic patients: A retrospective cohort study. Vaccine 2013; 31: 718-724.
5. American Diabetes Association. How many people need your help today? [Internet]. [cited 2017 Nov 6]. Available from: http://www.diabetes.org/
6. Prevention and control of influenza with vaccines: Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2010. MMWR Recomm. Rep. 2010, 59, 1–62.
7. The World health Organization. Influenza Vaccines; WHO Position Paper. Weekly Epidemiological Record. 23 Nov 2012. Available online: http://www.who.int/wer/en/ (accessed on 4 March 2015).
8. Santaularia J, Hou W, Perveen G, Welsh E, Faseru B. Prevalence of influenza vaccination and its association with health conditions and risk factors among Kansas adults in 2013: A cross-sectional study. BMC Public Health 2016; 16: 185.
9. Wang I, Lin C, Chang Y, Lin P, Liang C, Liu Y,et al. Effectiveness of influenza vaccination in elderly diabetic patients: A retrospective cohort study. Vaccine 2013; 31: 718-724.
10. American Diabetes Association. Standards of Medical Care in Diabetes-2015. Diabetes Care 2015, 38, 41-48.
11. Sato APS, Antunes JLF, Moura RF, de Andrade FB, Duarte YAO, Lebrão ML. Factors associated to vaccination against influenza among elderly in a large Brazilian metropolis. PLoS ONE 2015, 10, e0123840.
12.Ministry of Health, Kingdom of Saudi Arabia [Internet]. [cited 2017 Nov 6]. Available from: https://www.moh.gov. sa/ Pages/Default.aspx
13. Yeung MP, Lam FL, Coker R. Factors associated with the uptake of seasonal influenza vaccination in adults: a systematic review. J Public Health (Oxf). 2016 Dec 2;38(4):746-753. doi: 10.1093/pubmed/fdv194.
14. Kamimura A, Trinh HN, Weaver S, Chernenko A, Nourian MM, Assasnik N, et al. Knowledge and perceptions of influenza vaccinations among college students in Vietnam and the United States. J Prev Med Public Health. 2017 Jul;50(4):268-273. doi: 10.3961/jpmph.17.061.
15. Ma Y, Li T, Chen W, Chen J, Li M, Yang Z. Knowledge, Attitudes and Practices (KAP) toward seasonal influenza vaccine among young workers in South China. Hum VaccinImmunother. 2018 May 4;14(5):1283-1293. doi: 10.1080/ 21645515.2017.1423157
16. Macrotrends. Taif, Saudi Arabia population 1950-2019. Available at: https://www.macrotrends.net/cities/22434/taif/pop
17. Bartlett J. Kotrlik JW, Higgins CC. Organizational Research: Determining Appropriate Sample Size in Survey Research, 2001. Retrieved January 15, 2018 from: http://citeseerx.ist.psu.edu/viewdoc/download?doi =10.1.1. 486.8295&rep=rep1&type=pdf.
18. Bertoldo G, Pesce A, Pepe A, Pelullo CP, Di Giuseppe G, The Collaborative Working Group. Seasonal influenza: Knowledge, attitude and
vaccine uptake among adults with chronic conditions in Italy. PLoS ONE 2019; 14(5): e0215978. Available at: https://doi.org/10.1371/journal. pone. 0215978
19. WHO. Influenza (Seasonal). Available at: http://www.who.int/news-room/fact-sheets/detail/influenza-(seasonal).
20. Uyeki TM. Preventing and controlling influenza with available interventions. N Engl J Med. 2014;370:789–791. https://doi.org/10.1056/ NEJMp1400034 PMID: 24450860
21. Manzoli L, Ioannidis JP, Flacco ME, De Vito C, Villari P. Effectiveness and harms of seasonal and pandemic influenza vaccines in children, adults and elderly: a critical review and re-analysis of 15 metaanalyses. Hum Vaccin Immunother. 2012; 8:851–862. https://doi.org/10.4161/hv.19917 PMID:22777099
22. Manzoli L, De Vito C, Flacco ME, Marzuillo C, Boccia A, Villari P. Influenza vaccination recommended for all adults aged between 50 and 64 years: conceptual basis and methodological limitations. Ann Ig. 2012; 24:491–496, PMID: 23234186
23. Meier G, Gregg M, Poulsen Nautrup B. Cost-effectiveness analysis of quadrivalent influenza vaccination in at-risk adults and the elderly: an updated analysis in the U.K. J Med Econ. 2015; 18:746–761. https://doi.org/10.3111/13696998.2015.1044456 PMID: 25903831
24. Peasah SK, Azziz-Baumgartner E, Breese J, Meltzer MI, Widdowson MA. Influenza cost and costeffectiveness studies globally—a review. Vaccine. 2013; 31:5339–5348. https://doi.org/10.1016/j. vaccine.2013.09. 013 PMID: 24055351
25. Preaud E, Durand L, Macabeo B, Farkas N, Sloesen B, Palache A, et al. Vaccines Europe influenza working group. Annual public health and economic benefits of seasonal influenza vaccination: a European estimate. BMC Public Health. 2014; 14:813. https://doi.org/10.1186/1471-2458-14-813 PMID:25103091
26. Piano Nazionale Prevenzione Vaccinale 2017–1019. Available at: http://www.salute.gov.it/imgs/C_17_pubblicazioni_2571_allegato.pdf.
27. Estabragh ZR, Mamas MA. The cardiovascular manifestations of influenza: a systematic review. Int JCardiol. 2013; 167:2397–2403. https://doi.org/10.1016/j.ijcard.2013.01.274 PMID: 23474244
28. Joseph C, Togawa Y, Shindo N. Bacterial and viral infections associated with influenza. Influenza Other Respir Viruses. 2013; 7:105–113. https://doi.org/10.1111/irv.12089 PMID: 24034494
29. Jorgensen P, Mereckiene J, Cotter S, Johansen K, Tsolova S, Brown C. How close are countries of the WHO European Region to achieving the goal of vaccinating 75% of key risk groups against influenza? Results from national surveys on seasonal influenza vaccination programmes, 2008/2009 to 2014/2015. Vaccine. 2018; 36:442–452. https://doi.org/10. 1016/j.vaccine.2017.12.019 PMID: 29287683
30. Tuckerman JL, Collins JE, Marshall HS. Factors affecting uptake of recommended immunizations among health care workers in South Australia. Hum Vaccines Immunother. 2015; 11:704–712. https://doi.org/ 10.1080/21645515.2015.1008886 PMID: 25715003
31. Lu PJ, Srivastav A, Santibanez TA, Christopher Stringer M, Bostwick M, Dever JA, et al. Knowledge of influenza vaccination recommendation and early vaccination uptake during the 2015–16 season among adults aged ≥18years-United States. Vaccine. 2017; 35:4346–4354. https://doi.org/10.1016/j.vaccine. 2017.06.074 PMID: 28676381
32. Casalino E, Ghazali A, Bouzid D, Antoniol S, Pereira L, Kenway P, et al. Patient’s behaviors and missed opportunities for vaccination against seasonal epidemic influenza and evaluation of their impact on patient’s influenza vaccine uptake. PLoS One. 2018; 13:e:0193029. https://doi.org/10.1371/journal. pone.0193029 PMID: 29565990
33. Napolitano F, Napolitano P, Angelillo IF. Seasonal influenza vaccination in pregnant women: knowledge, attitudes, and behaviors in Italy. BMC Infect Dis. 2017; 17:48. https://doi.org/10.1186/s12879-016-2138-2 PMID: 28068918
34. Mertz D, Kim TH, Johnstone J, Lam PP, Science M, Kuster SP, et al. Populations at risk for severe or complicated influenza illness: systematic review and meta-analysis. BMJ. 2013; 347:f5061. https://doi.org/ 10.1136/ bmj.f5061 PMID: 23974637
35. Bodeker B, Remschmidt C, Schmich P, Wichmann O. Why are older adults and individuals with underlying chronic diseases in Germany not vaccinated against flu? A population-based study. BMC Public Health. 2015; 15:618. https://doi.org/10.1186/s12889-015-1970-4 PMID: 26148480
36. Olatunbosun OD, Esterhuizen TM, Wiysonge CS. A cross sectional survey to evaluate knowledge, attitudes and practices regarding seasonal influenza and influenza vaccination among diabetics in Pretoria, South Africa. Vaccine 2017;35: 6375-6386
37. Giese C, Mereckiene J, Danis K, O’Donnell J, O’Flanagan D, Cotter S. Low vaccination coverage for seasonal influenza and pneumococcal disease among adults at-risk and health care workers in Ireland, 2013: the key role of GPs in recommending vaccination. Vaccine. 2016; 34:3657–3662. https://doi.org/10.1016/j.vaccine.2016.05.028 PMID: 27255466
38. Ermenlieva NM, Tsankova GS, Todorova TT. Seasonal influenza vaccination: knowledge, attitude and practice in Varna, Bulgaria. Therapeutic Advances in Vaccines and Immunotherapy. 2019; 7: 1-9
DOI: 10.1177/2515135519868152
39. Salem SS, Miligi E, Alanazi HH, Alanazi NA, Alanazi AA. Knowledge and limitations associated with the uptake of seasonal Influenza vaccine among nursing students. International Journal of Novel Research in Healthcare and Nursing 2019;6(1):471-479.
40. Luz PM, Johnson RE, Brown HE. Workplace availability, risk group and perceived barriers predictive of 2016–17 influenza vaccine uptake in the United States: a cross-sectional study. Vaccine. 2017; 35:5890–5896. https://doi.org/10.1016/j.vaccine.2017.08.078 PMID: 28890192